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Correlation of enthesitis indices with disease activity and function in axial and peripheral spondyloarthritis: a cross-sectional study comparing MASES, SPARCC and LEI.
Palominos, Penélope Esther; de Campos, Ana Paula Beckhauser; Ribeiro, Sandra Lúcia Euzébio; Xavier, Ricardo Machado; Xavier, Jady Wroblewski; de Oliveira, Felipe Borges; Guerra, Bruno; Saldanha, Carla; Mancuso, Aline Castello Branco; Kohem, Charles Lubianca; Gasparin, Andrese Aline; Sampaio-Barros, Percival Degrava.
Afiliação
  • Palominos PE; Serviço de Reumatologia, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos 2350, sexto andar, Porto Alegre, Rio Grande do Sul, CEP 90035-903, Brazil. penelopepalominos@gmail.com.
  • de Campos APB; Serviço de Reumatologia, Hospital Universitário Evangélico, Alameda Augusto Stellfeld, 1908, Bigorrilho, Curitiba, Paraná, CEP 80730-150, Brazil.
  • Ribeiro SLE; Serviço de Reumatologia, Hospital Universitário Getúlio Vargas, Universidade Federal do Amazonas, Avenida Apurinã 4, Manaus, Amazonas, CEP 69020-170, Brazil.
  • Xavier RM; Serviço de Reumatologia, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos 2350, sexto andar, Porto Alegre, Rio Grande do Sul, CEP 90035-903, Brazil.
  • Xavier JW; Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2400, Porto Alegre, Rio Grande do Sul, CEP 90035-903, Brazil.
  • de Oliveira FB; Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2400, Porto Alegre, Rio Grande do Sul, CEP 90035-903, Brazil.
  • Guerra B; Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2400, Porto Alegre, Rio Grande do Sul, CEP 90035-903, Brazil.
  • Saldanha C; Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2400, Porto Alegre, Rio Grande do Sul, CEP 90035-903, Brazil.
  • Mancuso ACB; Serviço de Reumatologia, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos 2350, sexto andar, Porto Alegre, Rio Grande do Sul, CEP 90035-903, Brazil.
  • Kohem CL; Departamento de Bioestatística, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos 2350, Porto Alegre, Rio Grande do Sul, CEP 90035-903, Brazil.
  • Gasparin AA; Serviço de Reumatologia, Hospital de Clínicas de Porto Alegre, Ramiro Barcelos 2350, sexto andar, Porto Alegre, Rio Grande do Sul, CEP 90035-903, Brazil.
  • Sampaio-Barros PD; Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Ramiro Barcelos 2400, Porto Alegre, Rio Grande do Sul, CEP 90035-903, Brazil.
Adv Rheumatol ; 59(1): 23, 2019 06 17.
Article em En | MEDLINE | ID: mdl-31208465
BACKGROUND: The presence of enthesitis is associated with higher disease activity, more disability and incapacity to work and a poorer quality of life in spondyloarthritis (SpA). There is currently no consensus on which clinical score should be used to assess enthesitis in SpA. The objective of the present work was to compare the correlation of three enthesitis indices (MASES, SPARCC and LEI) with measures of disease activity and function in a heterogeneous population of patients with axial and peripheral SpA. METHODS: A cross-sectional study was conducted in three Brazilian public university hospitals; patients fulfilling ASAS classification criteria for peripheral or axial SpA were recruited and measures of disease activity and function were collected and correlated to three enthesitis indices: MASES, SPARCC and LEI using Spearman's Correlation index. ROC curves were used to determine if the the enthesitis indices were useful to discriminate patients with active disease from those with inactive disease. RESULTS: Two hundred four patients were included, 71.1% (N = 145) fulfilled ASAS criteria for axial SpA and 28.9% (N = 59) for peripheral SpA. In axial SpA, MASES performed better than LEI (p = 0.018) and equal to SPARCC (p = 0.212) regarding correlation with disease activity (BASDAI) and function (BASFI). In peripheral SpA, only MASES had a weak but statistical significant correlation with DAS28-ESR (rs 0.310 p = 0.05) and MASES had better correlation with functional measures (HAQ) than SPARCC (p = 0.034). CONCLUSION: In this sample composed of SpA patients with high coexistence of axial and peripheral features, MASES showed statistical significant correlation with measures of disease activity and function in both axial and peripheral SpA.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Índice de Gravidade de Doença / Espondilartrite / Entesopatia Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Adv Rheumatol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Índice de Gravidade de Doença / Espondilartrite / Entesopatia Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Adv Rheumatol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido