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Microsurgical Management of Trigeminal Schwannoma: Cohort Analysis and Systematic Review.
Neves, Maick Willen Fernandes; de Aguiar, Paulo Henrique Pires; Belsuzarri, Telmo Augusto Barba; de Araujo, André Monteiro Soares; Paganelli, Samantha Lorena; Maldaun, Marcos Vinicius Calfat.
Afiliação
  • Neves MWF; Department of Neurosurgery, Hospital Celso Pierro, Pontifícial Catholic University of Campinas, Campinas, São Paulo, Brazil.
  • de Aguiar PHP; Department of Neurosurgery, Pontifícial Catholic University of Sorocaba, Sorocaba, São Paulo, Brazil.
  • Belsuzarri TAB; Department of Neurosurgery, Hospital Celso Pierro, Pontifícial Catholic University of Campinas, Campinas, São Paulo, Brazil.
  • de Araujo AMS; Department of Neurosurgery, Pontifícial Catholic University of Campinas, Campinas, São Paulo, Brazil.
  • Paganelli SL; Department of Neurosurgery, Hospital Ramos Mejía, Buenos Aires University, CABA, Argentina.
  • Maldaun MVC; Department of Neurosurgery, Santa Paula Hospital, São Paulo, São Paulo, Brazil.
J Neurol Surg B Skull Base ; 80(3): 264-269, 2019 Jun.
Article em En | MEDLINE | ID: mdl-31143569
Background Trigeminal schwannomas are benign tumors with a predilection for women between 40 and 60 years of age and account for less than 0.5% of all intracranial tumors. Clinical presentation depends on size and location, and typical symptoms are ipsilateral hypesthesia, headache, and facial pain. Clinical features and imaging usually make the Diagnosis. Methods A retrospective cohort analysis of 14 patients treated at our institution between January 1999 and October 2016 was performed, with a critical and systematic review of data from the literature, focusing on articles published over the same period. Results Fourteen patients were included in our series comprised of mostly women with a mean age of 40 years. Lesion size ranged from 3 to 6.5 cm (mean 4.6 cm). Clinical status of patients was evaluated and also rated based on the Karnofsky Perfomance Scale with values greater than 90% found in all patients pre and postoperatively. Surgery was our treatment of choice, and gross total resection was achieved in 71% of patients. Associated morbidity was high at 57%, predominantly from cranial nerve palsy, and no deaths were encountered. Conclusions Microsurgery is a suitable treatment for large symptomatic trigeminal schwannomas, achieving good local control rates over the observation period at acceptable morbidity. Therefore, microsurgery appears to a suitable option. During the study period, a significant evolution in the availability of treatment methods occurred. Radiosurgery emerged as an alternative treatment for unresectable lesions. A comprehensive review of the available literature was performed, and results were compared according to treatment modality.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Risk_factors_studies / Systematic_reviews Idioma: En Revista: J Neurol Surg B Skull Base Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Risk_factors_studies / Systematic_reviews Idioma: En Revista: J Neurol Surg B Skull Base Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha