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Advances and potential application of gold nanoparticles in nanomedicine.
Lopes, Talíria Silva; Alves, Gutemberg Gomes; Pereira, Mariana Rodrigues; Granjeiro, Jose Mauro; Leite, Paulo Emílio Corrêa.
Afiliação
  • Lopes TS; Graduate Program in Sciences and Biotechnology, Fluminense Federal University - UFF, Niteroi, RJ, Brazil.
  • Alves GG; Cell and Molecular Biology Department, Biology Institute, Fluminense Federal University - UFF, Niteroi, RJ, Brazil.
  • Pereira MR; Biology Institute, Fluminense Federal University - UFF, Niteroi, RJ, Brazil.
  • Granjeiro JM; Dental School - Fluminense Federal University - UFF, Niteroi, RJ, Brazil.
  • Leite PEC; Laboratory of Bioengineering and in Vitro Toxicology, Directory of Metrology Applied to Life Sciences - Dimav, National Institute of Metrology Quality and Technology - INMETRO, Duque de Caxias, RJ, Brazil.
J Cell Biochem ; 120(10): 16370-16378, 2019 10.
Article em En | MEDLINE | ID: mdl-31127662
Nanomedicine is an emerging research area which has brought new possibilities and promising applications in image, diagnosis, and treatment. Nanoparticles (NPs) for medicinal purposes can be made of several material types such as silica, carbon, different polymers, and metals as silver, copper, titanium, and gold. Gold NPs (AuNPs) are the most studied and used, mostly due to their characteristics including simple preparation, controllable size and distribution, biocompatibility, good acceptance of surface modifications, and specific surface plasmon resonance (SPR). This study reviews the scientific literature regarding the potential applications of AuNPs in the development of new diagnostic and therapeutic strategies for nanomedicine, including their biomedical use as a drug carrier, as an agent in radio and phototherapy, and bioimaging for image diagnosis. While it becomes clear that much research remains to be done to improve the use of these nanoparticles, with particular concern for safety issues, the evidence from the literature already points to the great potential of AuNPs in nanomedicine.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanomedicina / Nanopartículas Metálicas / Ouro Limite: Humans Idioma: En Revista: J Cell Biochem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Nanomedicina / Nanopartículas Metálicas / Ouro Limite: Humans Idioma: En Revista: J Cell Biochem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos