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The combination of resveratrol and exercise enhances muscle growth characteristics in pacu (Piaractus mesopotamicus).
Salomão, Rondinelle Artur Simões; De Paula, Tassiana Gutierrez; Zanella, Bruna Tereza Thomazini; Carvalho, Pedro Luis Pucci Figueiredo; da Silva Duran, Bruno Oliveira; Valente, Jéssica Silvino; de Almeida Fantinatti, Bruno Evaristo; Fernandes, Ana Angélica; Barros, Margarida Maria; Mareco, Edson Assunção; Carvalho, Robson Francisco; Dos Santos, Vander Bruno; Dal-Pai-Silva, Maeli.
Afiliação
  • Salomão RAS; Department of Morphology, Institute of Bioscience, Sao Paulo State University, UNESP, Botucatu, SP, Brazil; Aquaculture Center, CAUNESP, Sao Paulo State University, UNESP, Jaboticabal, SP, Brazil.
  • De Paula TG; Department of Morphology, Institute of Bioscience, Sao Paulo State University, UNESP, Botucatu, SP, Brazil.
  • Zanella BTT; Department of Morphology, Institute of Bioscience, Sao Paulo State University, UNESP, Botucatu, SP, Brazil.
  • Carvalho PLPF; Department of Breeding and Animal Nutrition, FMVZ, Sao Paulo State University, UNESP, Botucatu, SP, Brazil.
  • da Silva Duran BO; Department of Morphology, Institute of Bioscience, Sao Paulo State University, UNESP, Botucatu, SP, Brazil.
  • Valente JS; Department of Morphology, Institute of Bioscience, Sao Paulo State University, UNESP, Botucatu, SP, Brazil.
  • de Almeida Fantinatti BE; Department of Morphology, Institute of Bioscience, Sao Paulo State University, UNESP, Botucatu, SP, Brazil.
  • Fernandes AA; Department of Chemistry and Biochemistry, Institute of Bioscience, Sao Paulo State University, UNESP, Botucatu, SP, Brazil.
  • Barros MM; Department of Breeding and Animal Nutrition, FMVZ, Sao Paulo State University, UNESP, Botucatu, SP, Brazil.
  • Mareco EA; Department of Biology, University of Western Sao Paulo, UNOESTE, Presidente Prudente, SP, Brazil.
  • Carvalho RF; Department of Morphology, Institute of Bioscience, Sao Paulo State University, UNESP, Botucatu, SP, Brazil.
  • Dos Santos VB; Sao Paulo Agency for Agribusiness Technology, APTA, Presidente Prudente, SP, Brazil.
  • Dal-Pai-Silva M; Department of Morphology, Institute of Bioscience, Sao Paulo State University, UNESP, Botucatu, SP, Brazil; Aquaculture Center, CAUNESP, Sao Paulo State University, UNESP, Jaboticabal, SP, Brazil. Electronic address: maeli.dal-pai@unesp.br.
Comp Biochem Physiol A Mol Integr Physiol ; 235: 46-55, 2019 09.
Article em En | MEDLINE | ID: mdl-31077846
Pacu is a tropical fish with important value to aquaculture. During cellular metabolism, reactive oxygen species (ROS) are produced, which can influence muscle growth. Resveratrol is an effective antioxidant that scavenges ROS and can modulate physical performance preventing oxidative stress. We investigated the effects of resveratrol and exercise on pacu muscle growth characteristics. Four groups were used: fish fed with control diet /without exercise (C); fish fed with control diet/subjected to exercise (CE); fish fed resveratrol-supplemented diet/without exercise (R); and fish fed resveratrol-supplemented diet/subjected to exercise (RE). At 30 days, the RE group presented a significant increase in body weight, fewer muscle fibers in the 20-40 µm and more fibers in the >60 µm diameter class compared to the C group. At day 7, catalase activity decreased in CE and RE groups. Superoxide dismutase activity decreased only in the CE group. Myod and mtor gene expression was higher in R and RE and igf-1 was up-regulated in the RE group. Murf1a level decreased in CE, R, and RE, while sdha expression was higher in the RE group. We suggest that resveratrol in combination with exercise was beneficial for muscle growth and metabolism, increasing the expression levels of genes related to muscle anabolism and oxidative metabolism, besides the decrease of catabolic gene expression. Notably, all of these changes occurred together with muscle hypertrophy and increased body weight. Our results show a positive application for resveratrol in association with exercise as a strategy to improve the growth performance of juvenile pacus.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Músculo Esquelético / Caraciformes / Resveratrol / Antioxidantes Limite: Animals / Humans Idioma: En Revista: Comp Biochem Physiol A Mol Integr Physiol Assunto da revista: BIOLOGIA MOLECULAR / FISIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Músculo Esquelético / Caraciformes / Resveratrol / Antioxidantes Limite: Animals / Humans Idioma: En Revista: Comp Biochem Physiol A Mol Integr Physiol Assunto da revista: BIOLOGIA MOLECULAR / FISIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos