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Occult central pontine myelinolysis post liver transplant: A consequence of pre-transplant hyponatremia.
Zhu, Julie; Al-Alkim, Fatema; Hussaini, Trana; Vertinsky, Alexandra; Byrne, Danielle; Erb, Siegfried R; Stoessl, A Jon; Yoshida, Eric M.
Afiliação
  • Zhu J; Department of Medicine, Division of Gastroenterology, University of British Columbia, Vancouver, Canada.
  • Al-Alkim F; Department of Medicine, Division of Gastroenterology, University of British Columbia, Vancouver, Canada.
  • Hussaini T; Faculty of Pharmaceutical Sciences, The University of British Columbia, Vancouver, Canada.
  • Vertinsky A; Department of Radiology, University of British Columbia, Vancouver, Canada.
  • Byrne D; Department of Radiology, University of British Columbia, Vancouver, Canada.
  • Erb SR; Department of Medicine, Division of Gastroenterology, University of British Columbia, Vancouver, Canada.
  • Stoessl AJ; Department of Neurology, University of British Columbia, Vancouver, Canada.
  • Yoshida EM; Department of Medicine, Division of Gastroenterology, University of British Columbia, Vancouver, Canada. Electronic address: eric.yoshida@vch.ca.
Ann Hepatol ; 18(4): 651-654, 2019.
Article em En | MEDLINE | ID: mdl-31056363
Rapid overcorrection of chronic hyponatremia can lead to osmotic demyelination syndrome or central pontine myelinolysis (CPM), a diagnosis often triggered by observing the characteristics of neurological abnormalities developed as a result of CPM. However, anyone with chronic hyponatremia and overcorrection of serum sodium is at risk of physiological CPM despite the lack of clinical symptoms. We report an adult patient who presented as post-op delirium, had incidental finding of CPM by magnetic resonance imaging (MRI) of the head after a liver transplant. Despite his non-typical presentation, the patient had the typical risk factors of CPM such as chronic hyponatremia, rapid overcorrection of serum sodium and cirrhosis undergoing a transplant. As hyponatremia and neurological disorder such encephalopathy simultaneously affect patients with cirrhosis, CPM may be more common than once thought in the chronic liver disease population and inappropriate hyponatremia management has important medical consequences that can go unnoticed.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações Pós-Operatórias / Transplante de Fígado / Mielinólise Central da Ponte / Delírio / Achados Incidentais / Hidratação / Hiponatremia / Cirrose Hepática Biliar Tipo de estudo: Diagnostic_studies / Etiology_studies / Risk_factors_studies Limite: Humans / Male / Middle aged Idioma: En Revista: Ann Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Canadá País de publicação: México
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Complicações Pós-Operatórias / Transplante de Fígado / Mielinólise Central da Ponte / Delírio / Achados Incidentais / Hidratação / Hiponatremia / Cirrose Hepática Biliar Tipo de estudo: Diagnostic_studies / Etiology_studies / Risk_factors_studies Limite: Humans / Male / Middle aged Idioma: En Revista: Ann Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Canadá País de publicação: México