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Time spent on erythropoietin stimulating agents administration in hemodialysis centers in Panama: a time and motion study.
Chacón-Araya, Marianne; Rey-Rodríguez, Diego; Rodríguez De León, Felipe; Ramos-Esquivel, Allan; Sunning, Tao.
Afiliação
  • Chacón-Araya M; a Roche Central America & Caribbean , Heredia , Costa Rica.
  • Rey-Rodríguez D; b Department of Nephrology , Hospital Santo Tomás , Panama , Panama.
  • Rodríguez De León F; c Caja de Seguro Social , Complejo Hospitalario Dr. Arnulfo Arias Madrid , Panama , Panama.
  • Ramos-Esquivel A; d Department of Pharmacology School of Medicine , University of Costa Rica , San José , Costa Rica.
  • Sunning T; e United BioSource Corporation , Montreal , Canada.
J Med Econ ; 22(8): 736-741, 2019 Aug.
Article em En | MEDLINE | ID: mdl-30915883
Objectives: There is a lack of data in Panama on the potential differences in total healthcare professional (HCP) time between routine administrations of short-acting erythropoietin simulating agents (ESAs) (i.e. epoetin alfa) and continuous erythropoietin receptor activator (CERA) (i.e. methoxy polyethylene glycol-epoetin beta). This study aimed to quantify the HCP time associated with a single administration of epoetin alfa and CERA for the treatment of anemic patients with chronic kidney disease (CKD) on hemodialysis. Methods: This was a multi-center, cross-sectional study, using a time-and-motion methodology. Costs related to HCP time and consumables usage associated with administration of epoetin alfa and CERA were estimated. Results: Based on 60 administrations of either CERA or epoetin alfa, the estimated savings in mean total active HCP time were 2.34 (95% confidence interval = 1.87-2.81) min (-30%) per administration. When extrapolating to a full year's treatment with intravenous ESA, it would require a total of 20.3 (95% CI = 19.90-20.71) h of HCP time for epoetin alfa vs 1.1 (95% CI = 1.01-1.19) h for CERA per patient per year. Estimated savings in active HCP time per patient per year were 19.20 (95% CI = 19.20-19.21) h (-95%). This, in turn, translates into staff cost efficiency that favors Mircera with an estimated annual saving of $78.24 (95% CI = 78.24-78.28) (-95%) per patient. Conclusions: Data from a real-world setting showed that the adoption of CERA could potentially lead to a reduction in active HCP time. Highlights Few comparative data have explored the costs and potential savings of using long-acting erythropoietin-stimulating agents (ESA) instead of short-acting ESAs to treat anemia in CKD patients on hemodialysis. This time-and-motion study shows that use of CERA reduces total healthcare professional time and could represent a save for an institution in a real-world setting in Panama.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoglicóis / Eritropoetina / Pessoal de Saúde / Epoetina alfa / Hematínicos Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Female / Humans / Male País/Região como assunto: America central / Panama Idioma: En Revista: J Med Econ Assunto da revista: SERVICOS DE SAUDE Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Costa Rica País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polietilenoglicóis / Eritropoetina / Pessoal de Saúde / Epoetina alfa / Hematínicos Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Female / Humans / Male País/Região como assunto: America central / Panama Idioma: En Revista: J Med Econ Assunto da revista: SERVICOS DE SAUDE Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Costa Rica País de publicação: Reino Unido