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Assessment and Impact of Cognitive Impairment in Multiple Sclerosis: An Overview.
Macías Islas, Miguel Ángel; Ciampi, Ethel.
Afiliação
  • Macías Islas MÁ; Department of Neurosciences, CUCS. University of Guadalajara and Mexico, Guadalajara 44160, Mexico. miguelangelmacias@hotmail.com.
  • Ciampi E; Neurology, Pontificia Universidad Católica de Chile, Neurology, Hospital Dr. Sótero del Río, Santiago 8320000, Chile. ethelciampi@gmail.com.
Biomedicines ; 7(1)2019 Mar 19.
Article em En | MEDLINE | ID: mdl-30893874
Cognitive impairment affects 40⁻60% of patients with multiple sclerosis. It may be present early in the course of the disease and has an impact on a patient's employability, social interactions, and quality of life. In the last three decades, an increasing interest in diagnosis and management of cognitive impairment has arisen. Neuropsychological assessment and neuroimaging studies focusing on cognitive impairment are now being incorporated as primary outcomes in clinical trials. However, there are still key uncertainties concerning the underlying mechanisms of damage, neural basis, sensitivity and validity of neuropsychological tests, and efficacy of pharmacological and non-pharmacological interventions. The present article aimed to present an overview of the assessment, neural correlates, and impact of cognitive impairment in multiple sclerosis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Aspecto: Patient_preference Idioma: En Revista: Biomedicines Ano de publicação: 2019 Tipo de documento: Article País de afiliação: México País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Aspecto: Patient_preference Idioma: En Revista: Biomedicines Ano de publicação: 2019 Tipo de documento: Article País de afiliação: México País de publicação: Suíça