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Application of a novel sex independent anthropometric index, termed angle index, in relation to type 2 diabetes: a Trinidadian case-control study.
Ramnanansingh, Terry Gavaskar; Nayak, Shivananda Bijoor.
Afiliação
  • Ramnanansingh TG; School of Pharmacy, Faculty of Medical Sciences, The University of the West Indies, St Augustine, Trinidad and Tobago.
  • Nayak SB; Biochemistry Unit, Department of Preclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St Augustine, Trinidad and Tobago.
BMJ Open ; 9(2): e024029, 2019 02 19.
Article em En | MEDLINE | ID: mdl-30782890
OBJECTIVE: To develop a novel sex independent anthropometric index, termed as angle index, related to type 2 diabetes. DESIGN: Case-control. PARTICIPANTS: The study comprised 121 participants and were divided into two groups. One group had no form of diabetes and served as controls (n=50). The other group had the condition of type 2 diabetes (n=71). 31% (n=37) of the subjects were male and 69% (n=84) were female. 62% (n=75) of the subjects were of East Indian ethnicity, 28% (n=34) were of African ethnicity and 10% (n=12) were of mixed ethnicity. SETTING: Participants of the study were from the island of Trinidad, located in the Caribbean. Patients in the study were selected at random from hospital records. PRIMARY OUTCOME MEASURE: It was hypothesised that the mean angle index of patients with type 2 diabetes would be higher than the mean angle index of patients without type 2 diabetes. RESULTS: Patients with type 2 diabetes had a significantly higher angle index value as compared with controls (p<0.001). Angle index was the superior sex independent anthropometric index in relation to type 2 diabetes (area under the curve=0.72; p<0.001) as compared with other sex independent variables. Angle index correlated with glycated haemoglobin (rs=0.28, p=0.003) and fasting blood glucose (rs=0.31, p=0.001) levels. Patients with type 2 diabetes were four times more likely to have an angle index greater than 184° (OR 4.2, 95% CI 1.8 to 9.9) as compared with controls. CONCLUSION: Angle index was a superior sex independent index for discriminating between patients with and without type 2 diabetes, as compared with waist circumference, abdominal volume index, conicity index, blood pressure readings, triglyceride levels and very low-density lipoprotein levels.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antropometria / Diabetes Mellitus Tipo 2 / Obesidade Abdominal Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: Caribe ingles / Trinidad y tobago Idioma: En Revista: BMJ Open Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Trinidad e Tobago País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antropometria / Diabetes Mellitus Tipo 2 / Obesidade Abdominal Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: Caribe ingles / Trinidad y tobago Idioma: En Revista: BMJ Open Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Trinidad e Tobago País de publicação: Reino Unido