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Adherence and quality of life in women with breast cancer being treated with oral hormone therapy.
Stahlschmidt, Rebeca; Ferracini, Amanda Canato; de Souza, Cinthia Madeira; de Medeiros, Luana Moreira; Juliato, Cassia Raquel Teatin; Mazzola, Priscila Gava.
Afiliação
  • Stahlschmidt R; Faculty of Medical Sciences, University of Campinas (Unicamp), Tessália Vieira de Camargo Street, 126, Cidade Universitária "Zeferino Vaz", Campinas, SP, 13083-887, Brazil.
  • Ferracini AC; Faculty of Medical Sciences, University of Campinas (Unicamp), Tessália Vieira de Camargo Street, 126, Cidade Universitária "Zeferino Vaz", Campinas, SP, 13083-887, Brazil.
  • de Souza CM; Faculty of Medical Sciences, University of Campinas (Unicamp), Tessália Vieira de Camargo Street, 126, Cidade Universitária "Zeferino Vaz", Campinas, SP, 13083-887, Brazil. cinthiacms@gmail.com.
  • de Medeiros LM; Faculty of Pharmaceutical Sciences, University of Campinas (Unicamp), Cândido Portinari Street, 200, Cidade Universitária "Zeferino Vaz", Campinas, SP, 13083-871, Brazil.
  • Juliato CRT; Faculty of Medical Sciences, University of Campinas (Unicamp), Tessália Vieira de Camargo Street, 126, Cidade Universitária "Zeferino Vaz", Campinas, SP, 13083-887, Brazil.
  • Mazzola PG; Faculty of Pharmaceutical Sciences, University of Campinas (Unicamp), Cândido Portinari Street, 200, Cidade Universitária "Zeferino Vaz", Campinas, SP, 13083-871, Brazil.
Support Care Cancer ; 27(10): 3799-3804, 2019 Oct.
Article em En | MEDLINE | ID: mdl-30729297
PURPOSE: To evaluate adherence to oral hormone therapy (HT) and which factors impact in incomplete adherence and quality of life. METHODS: This was a cross-sectional study. SETTING: Women's Hospital Prof. Dr. José Aristodemo Pinotti. PARTICIPANTS: women with breast cancer under treatment with oral HT. MAIN OUTCOME MEASURES: interview and performed an adherence questionnaire (Morisky-Green) and two questionnaires of quality of life (EORTC-QLQ30/BR23). The interviews were done once in a 5-month period. RESULTS: Fifty-eight women were interviewed: 42 under treatment with tamoxifen (TX) and 16 under treatment with aromatase inhibitor (AI). Twenty-six women (44%) showed high adherence to the treatment, 31 (54%) medium adherence, and 1 (2%) low adherence. Statistical analysis showed a relation between incomplete adherence and systemic therapy side effects as well as higher stages of disease, with no difference between the two drugs. When treatments were compared, this study showed treatment with AI presented less breast symptoms and better role functioning. Quality of life score was high, compared to the reference value. CONCLUSIONS: A low percentage of women with breast cancer were highly adherent to HT treatment. Low/medium adherence was associated with higher stages of disease and systemic side effects. Quality of life had high scores, with better role function and less breast symptoms in women being treated with an AI.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Tamoxifeno / Neoplasias da Mama / Antineoplásicos Hormonais / Inibidores da Aromatase / Cooperação e Adesão ao Tratamento Tipo de estudo: Observational_studies / Prevalence_studies / Qualitative_research / Risk_factors_studies Aspecto: Patient_preference Limite: Female / Humans / Middle aged Idioma: En Revista: Support Care Cancer Assunto da revista: NEOPLASIAS / SERVICOS DE SAUDE Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Tamoxifeno / Neoplasias da Mama / Antineoplásicos Hormonais / Inibidores da Aromatase / Cooperação e Adesão ao Tratamento Tipo de estudo: Observational_studies / Prevalence_studies / Qualitative_research / Risk_factors_studies Aspecto: Patient_preference Limite: Female / Humans / Middle aged Idioma: En Revista: Support Care Cancer Assunto da revista: NEOPLASIAS / SERVICOS DE SAUDE Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Alemanha