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High Prevalence of Diabetes Mellitus in a Cohort of Patients with Chronic Obstructive Pulmonary Disease in Trinidad, West Indies.
Rambaran, Kirin; Bhagan, Bryan; Ali, Amanda; Ali, Firas; Toolsie, Shivan; Lobin, Rekha; Beharry, Shivani; Ghany, Sabrina; Mohammed, Saeeda; Davis, Gershwin; Sakhamuri, Sateesh; Teelucksingh, Surujpal; Seemungal, Terence.
Afiliação
  • Rambaran K; Department of Clinical Medical Sciences, Faculty of Medical Sciences, the University of the West Indies (St Augustine Campus), Trinidad and Tobago.
  • Bhagan B; Department of Clinical Medical Sciences, Faculty of Medical Sciences, the University of the West Indies (St Augustine Campus), Trinidad and Tobago.
  • Ali A; Department of Clinical Medical Sciences, Faculty of Medical Sciences, the University of the West Indies (St Augustine Campus), Trinidad and Tobago.
  • Ali F; Department of Clinical Medical Sciences, Faculty of Medical Sciences, the University of the West Indies (St Augustine Campus), Trinidad and Tobago.
  • Toolsie S; Department of Clinical Medical Sciences, Faculty of Medical Sciences, the University of the West Indies (St Augustine Campus), Trinidad and Tobago.
  • Lobin R; Department of Clinical Medical Sciences, Faculty of Medical Sciences, the University of the West Indies (St Augustine Campus), Trinidad and Tobago.
  • Beharry S; Department of Clinical Medical Sciences, Faculty of Medical Sciences, the University of the West Indies (St Augustine Campus), Trinidad and Tobago.
  • Ghany S; Department of Clinical Medical Sciences, Faculty of Medical Sciences, the University of the West Indies (St Augustine Campus), Trinidad and Tobago.
  • Mohammed S; Department of Clinical Medical Sciences, Faculty of Medical Sciences, the University of the West Indies (St Augustine Campus), Trinidad and Tobago.
  • Davis G; Department of Para-clinical Sciences, Faculty of Medical Sciences, the University of the West Indies (St Augustine Campus), Trinidad and Tobago.
  • Sakhamuri S; Department of Clinical Medical Sciences, Faculty of Medical Sciences, the University of the West Indies (St Augustine Campus), Trinidad and Tobago.
  • Teelucksingh S; Department of Clinical Medical Sciences, Faculty of Medical Sciences, the University of the West Indies (St Augustine Campus), Trinidad and Tobago.
  • Seemungal T; Department of Clinical Medical Sciences, Faculty of Medical Sciences, the University of the West Indies (St Augustine Campus), Trinidad and Tobago.
Turk Thorac J ; 20(1): 12-17, 2019 Jan 01.
Article em En | MEDLINE | ID: mdl-30664421
OBJECTIVES: Both chronic obstructive pulmonary disease (COPD) and diabetes mellitus (DM) are highly prevalent in Trinidad, West Indies. Our objective was to evaluate the prevalence of DM in a cohort of Trinidadian patients with COPD and investigate the possible impact of diabetes on COPD using standard outcome measures, that is, lung function, exacerbations, quality of life and depression questionnaires, as well as mortality. MATERIALS AND METHODS: This was a cross-sectional follow-up study utilizing a cohort of 105 patients from chest clinics in the three major general hospitals in Trinidad. RESULTS: Diabetes was diagnosed based on a glycated hemoglobin (HbA1c) level of ≥6.5% (or a prior self-reported history), and for pre-diabetes, of 5.7%-6.4%. Of 105 patients, 40% fulfilled the criteria for diabetes and 40% for pre-diabetes. Of those diagnosed with diabetes, 38% obtained this diagnosis de novo. A history of intravenous corticosteroid use was associated with higher HbA1c levels (p=0.043) upon diagnosis. The percentage of predicted forced vital capacity was negatively related to HbA1c (p=0.033), but those with diabetes also had a greater body mass index (p=0.001). After a 1-year follow-up, mortality was significantly greater among patients with diabetes (p=0.026). Patients with at least one exacerbation in the past year or poorer lung function parameters had worse quality of life (p≤0.040) and depression (p≤0.018) scores. Notably, 31.4% of the total cohort exhibited clinically significant depression scores. CONCLUSION: This study revealed that a high proportion of COPD patients in tertiary care had diabetes or pre-diabetes.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference País/Região como assunto: Caribe Idioma: En Revista: Turk Thorac J Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Trinidad e Tobago País de publicação: Turquia
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference País/Região como assunto: Caribe Idioma: En Revista: Turk Thorac J Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Trinidad e Tobago País de publicação: Turquia