Moderate-to-high intensity inspiratory muscle training improves the effects of combined training on exercise capacity in patients after coronary artery bypass graft surgery: A randomized clinical trial.
Int J Cardiol
; 279: 40-46, 2019 Mar 15.
Article
em En
| MEDLINE
| ID: mdl-30581100
BACKGROUND: The effects of adding moderate-to-high intensity inspiratory muscle training (IMT) to short-term aerobic and resistance exercise (combined training [CT]), after coronary artery bypass grafting (CABG) are not established. This study aimed to determine the effects of moderate-to-high intensity IMTâ¯+â¯CT on exercise capacity, respiratory muscle strength, inspiratory muscle endurance, quality of life (QoL), and laboratory biomarkers in patients after CABG who were participants of a phase II cardiac rehabilitation program. METHODS: Twenty-four patients were randomly assigned to either the IMTâ¯+â¯CT group (nâ¯=â¯12), who performed moderate-to-high intensity IMT with CT or the sham-IMTâ¯+â¯CT group (nâ¯=â¯12). Patients completed two sessions per week for 12â¯weeks. Each patient underwent a cardiopulmonary exercise test, six-minute walk test (6MWT), respiratory muscle strength and endurance evaluation, QoL questionnaire, and serum advanced oxidation protein products, ferric reducing antioxidant power [FRAP], nitrate/nitrate, and high-sensitivity C-reactive protein, before and after the 12-week intervention. RESULTS: The IMTâ¯+â¯CT group showed significantly greater improvements in peak oxygen uptake (1.3â¯mLâkg-1âmin-1; 95% confidence interval [95% CI], 0.5 to 2.2), distance covered during the 6MWT (78.8â¯m; 95% CI, 28.1 to 129.5), maximal inspiratory pressure (23.0 cmH2O; 95% CI, 9.3 to 36.7), QoL (-15.1 points; 95% CI, -26.9 to -3.3), and FRAP (83.7⯵mol/L; 95% CI, 20.2 to 147.1) compared to the sham-IMTâ¯+â¯CT group as a result of the intervention. CONCLUSIONS: Short-term moderate-to-high intensity IMT with CT provided additional benefits in exercise capacity, inspiratory muscle strength, QoL, and antioxidant profile in patients after CABG. Trial Registration clinicaltrials.gov Identifier: NCT02885077.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Resistência Física
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Músculos Respiratórios
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Exercícios Respiratórios
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Exercício Físico
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Inalação
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Ponte de Artéria Coronária
Tipo de estudo:
Clinical_trials
Aspecto:
Patient_preference
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Int J Cardiol
Ano de publicação:
2019
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Holanda