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The antibacterial effect of potassium-sodium niobate ceramics based on controlling piezoelectric properties.
Yao, Tiantian; Chen, Junqi; Wang, Zhengao; Zhai, Jinxia; Li, Yangfan; Xing, Jun; Hu, Shiqian; Tan, Guoxin; Qi, Suijian; Chang, Yunbing; Yu, Peng; Ning, Chengyun.
Afiliação
  • Yao T; School of Material Science and Engineering & School of Biomedical Science and Engineering, South China University of Technology, Guangzhou 510006, PR China; National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, PR
  • Chen J; School of Material Science and Engineering & School of Biomedical Science and Engineering, South China University of Technology, Guangzhou 510006, PR China; National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, PR
  • Wang Z; School of Material Science and Engineering & School of Biomedical Science and Engineering, South China University of Technology, Guangzhou 510006, PR China; National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, PR
  • Zhai J; School of Material Science and Engineering & School of Biomedical Science and Engineering, South China University of Technology, Guangzhou 510006, PR China; National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, PR
  • Li Y; School of Material Science and Engineering & School of Biomedical Science and Engineering, South China University of Technology, Guangzhou 510006, PR China; National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, PR
  • Xing J; School of Material Science and Engineering & School of Biomedical Science and Engineering, South China University of Technology, Guangzhou 510006, PR China; National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, PR
  • Hu S; School of Material Science and Engineering & School of Biomedical Science and Engineering, South China University of Technology, Guangzhou 510006, PR China; National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, PR
  • Tan G; School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou 510006, PR China.
  • Qi S; School of Food Science and Engineering, South China University of Technology, Guangzhou 510006, PR China. Electronic address: 20953987@qq.com.
  • Chang Y; Orthopedic Department, Guangdong General Hospital (Guangdong Academy of Medical Sciences), Guangzhou 510006, PR China. Electronic address: cspine@qq.com.
  • Yu P; School of Material Science and Engineering & School of Biomedical Science and Engineering, South China University of Technology, Guangzhou 510006, PR China; National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, PR
  • Ning C; School of Material Science and Engineering & School of Biomedical Science and Engineering, South China University of Technology, Guangzhou 510006, PR China; National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, PR
Colloids Surf B Biointerfaces ; 175: 463-468, 2019 Mar 01.
Article em En | MEDLINE | ID: mdl-30572154
The implant infection is one of the most serious postsurgical complications of medical device implantation. Therefore, the development of biocompatible materials with improved antibacterial properties is of great importance. It might be a new insight to apply the intrinsic electrical properties of biomaterials to solve this problem. Here, potassium-sodium niobate piezoceramics (K0.5Na0.5NbO3, KNN) with different piezoelectric constants were prepared, and the microstructures and piezoelectric properties of these piezoceramics were evaluated. Moreover, the antibacterial effect and biocompatibility of these piezoceramics were assayed. Results showed that these piezoceramics were able to decrease the colonies of bacteria staphylococcus aureus (S. aureus), favor the rat bone marrow mesenchymal stem cells (rBMSCs) proliferation and promote the cell adhesion and spreading. The above effects were found closely related to the surface positive charges of the piezoceramics, and the sample bearing the most positive charges on its surface (sample 80KNN) had the best performance in both antibacterial effect and biocompatibility. Based on our work, it is feasible to develop biocompatible antibacterial materials by controlling piezoelectric properties.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Óxidos / Potássio / Sódio / Staphylococcus aureus / Cerâmica / Impedância Elétrica / Células-Tronco Mesenquimais / Antibacterianos / Nióbio Limite: Animals Idioma: En Revista: Colloids Surf B Biointerfaces Assunto da revista: QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Óxidos / Potássio / Sódio / Staphylococcus aureus / Cerâmica / Impedância Elétrica / Células-Tronco Mesenquimais / Antibacterianos / Nióbio Limite: Animals Idioma: En Revista: Colloids Surf B Biointerfaces Assunto da revista: QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de publicação: Holanda