Your browser doesn't support javascript.
loading
Comparative Pharmacognosy, Chemical Profile and Antioxidant Activity of Extracts from Phania matricarioides (Spreng.) Griseb. Collected from Different Localities in Cuba.
Gutiérrez, Yamilet I; Scull, Ramón; Monzote, Lianet; Rodríguez, Katia M; Bello, Adonis; Setzer, William N.
Afiliação
  • Gutiérrez YI; Department of Chemistry, Institute of Pharmacy and Food, Havana University, Coronela, Lisa, Havana 13600, Cuba. ygutierrez@infomed.sld.cu.
  • Scull R; Department of Chemistry, Institute of Pharmacy and Food, Havana University, Coronela, Lisa, Havana 13600, Cuba. rscull@ifal.uh.cu.
  • Monzote L; Parasitology Department, Institute of Tropical Medicine "Pedro Kouri", Havana 10400, Cuba. monzote@ipk.sld.cu.
  • Rodríguez KM; Centro de Inmunología Molecular, Havana 10400, Cuba. katiam@cim.sld.cu.
  • Bello A; Facultad de Ciencias Químicas, Universidad de Guayaquil, P.O. Box 0901-5738, Guayaquil 090514, Ecuador. adonisbello@gmail.com.
  • Setzer WN; Department of Chemistry, University of Alabama in Huntsville, Huntsville, AL 35899, USA. wsetzer@chemistry.uah.edu.
Plants (Basel) ; 7(4)2018 Dec 14.
Article em En | MEDLINE | ID: mdl-30558108
Phania matricarioides (Spreng.) Griseb. is a traditionally used plant with various pharmacological properties. However, there are only scarce reports about the phytochemistry and biological activity of this plant. In this work, P. matricarioides was collected from three different localities of Cuba: PmB (collected in Bauta, Artemisa), PmC (collected in Cangrejeras, Artemisa), and PmI (collected in La Lisa, Havana), extracted with aqueous ethanol, and analyzed macroscopically and microscopically. The extracts were screened for phytochemical contents, analyzed by TLC and HPLC, and screened for antioxidant activity using the FRAP and DPPH assays. Macroscopic analysis showed similar results for all samples; however, microscopic, physicochemical and phytochemical studies showed appreciable differences. In particular, the total solid of PmC extract was higher (1.94 ± 0.03%) than the other samples. In HPLC profiles, quercetin was identified in the three samples and a greater similarity between samples PmB and PmI was observed. All samples demonstrated radical-scavenging antioxidant activity by the DPPH assay, which PmC also demonstrated the smaller (p < 0.05) value (IC50 = 27.4 ± 0.1 µg/mL), but was statistically superior (p < 0.05) to vitamin C (IC50 = 23.7 ± 0 µg/mL). Also, in the FRAP assay, a higher vitamin C equivalent of PmC was significantly superior (p < 0.05) to the other extracts at the evaluated concentrations, which is likely due to a higher concentration of quercetin. In conclusion, P. matricarioides could constitute a potential resource in the field of phytotherapeutic products, and the results obtained can contribute to the development of the quality control norms for this species.
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE País/Região como assunto: Cuba Idioma: En Revista: Plants (Basel) Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Cuba País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE País/Região como assunto: Cuba Idioma: En Revista: Plants (Basel) Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Cuba País de publicação: Suíça