Updates in the Diagnosis and Treatment of Paraneoplastic Neurologic Syndromes.
Curr Oncol Rep
; 20(11): 92, 2018 11 10.
Article
em En
| MEDLINE
| ID: mdl-30415318
The disorders of the central nervous system associated with cancer by remote immune-mediated mechanisms are a heterogeneous group. These disorders encompass the classic paraneoplastic disorders and the recently recognized autoimmune encephalitis associated with antibodies against neuronal cell surface or synaptic proteins that occur with or without cancer association. In the last decade, the new surge of interest in neuronal diseases associated with anti-neuronal antibodies led to the rapid discovery of new forms of disease that have different manifestations and were not previously suspected to be immune mediated. The recognition of these syndromes is important because it may lead to early detection of an underlying malignancy and prompt initiation of treatment, improving chances for a better outcome.
Palavras-chave
Anti-AMPA receptor (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) encephalitis; Anti-CV2/CRMP5 antibodies; Anti-Caspr2 encephalitis (contactin-associated protein-like 2); Anti-DNER (Delta/Notch-like epidermal growth factor-related receptor) antibodies; Anti-GABAbR (γ-aminobutyric acid receptor-B) encephalitis; Anti-Hu antibodies; Anti-Ma2 antibodies; Anti-glycine receptor (GlyR) antibodies; Anti-leucine-rich glioma-inactivated protein 1 (LGI1) encephalitis; Anti-mGLUR1 (metabotropic glutamate receptor 1); Anti-mGluR5 (metabotropic glutamate receptor 5); Autoimmune encephalitis; Limbic encephalitis; Morvan syndrome; N-methyl-D-aspartate receptor (NMDAR) encephalitis; Onconeuronal antibodies; Ophelia syndrome; Opsoclonus-myoclonus syndrome; Paraneoplastic cerebellar degeneration; Paraneoplastic encephalomyelitis; Paraneoplastic neurological syndromes; Progressive encephalomyelitis with rigidity and myoclonus; Stiff person syndrome
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças do Sistema Nervoso Central
/
Síndromes Paraneoplásicas do Sistema Nervoso
/
Encefalite
/
Doença de Hashimoto
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Limite:
Humans
Idioma:
En
Revista:
Curr Oncol Rep
Assunto da revista:
NEOPLASIAS
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Estados Unidos