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The use of probiotics for improving lipid profiles in dyslipidemic individuals: an overview protocol.
Fortes, Patricia M; Marques, Solomar M; Viana, Karolline A; Costa, Luciane R; Naghettini, Alessandra V; Costa, Paulo Sucasas.
Afiliação
  • Fortes PM; Health Sciences Graduate Program, Medicine School, Universidade Federal de Goiás (UFG), Rua 235, s/n, Setor Leste Universitário, Goiânia, GO, CEP 74605-050, Brazil.
  • Marques SM; Department of Pediatrics, Hospital das Clinicas, UFG, Primeira Avenida, s/n, Setor Leste Universitário, Goiânia, GO, CEP 74605-020, Brazil.
  • Viana KA; Department of Pediatrics, Hospital das Clinicas, UFG, Primeira Avenida, s/n, Setor Leste Universitário, Goiânia, GO, CEP 74605-020, Brazil.
  • Costa LR; Dentistry Graduate Program, UFG, Primeira Avenida, s/n, esquina com Praça Universitária, Setor Leste Universitário, Goiânia, GO, CEP 74605-220, Brazil.
  • Naghettini AV; Dentistry Graduate Program, UFG, Primeira Avenida, s/n, esquina com Praça Universitária, Setor Leste Universitário, Goiânia, GO, CEP 74605-220, Brazil.
  • Costa PS; Division of Pediatric Dentistry, Faculdade de Odontologia, UFG, Primeira Avenida, s/n, esquina com Praça Universitária, Setor Leste Universitário, Goiânia, GO, CEP 74605-220, Brazil.
Syst Rev ; 7(1): 165, 2018 10 17.
Article em En | MEDLINE | ID: mdl-30326965
BACKGROUND: Dyslipidemia is a major risk factor in triggering cardiovascular events, which can lead to the death of millions of people around the world. Thus, several pharmacological and non-pharmacological therapeutic strategies have been developed in recent decades with the objective of improving lipid profiles, including the use of probiotics. Therefore, the purpose of this protocol is to describe the steps that will guide the construction of an overview to demonstrate the scientific evidence of the efficacy of probiotics in improving the lipid profile of dyslipidemic individuals and to propose specific recommendations regarding their use. METHODS: The search will be conducted in the following databases: MEDLINE/PubMed, EMBASE, PROSPERO, Cochrane Library, CINAHL, JBI Database of Systematic Reviews and Implementation Reports, Google Scholar, and CADTH. Reviewers will select systematic evaluations and data analyses from randomized clinical trials that evaluated the effects of probiotics on lipid profiles. The studies will be analyzed for methodology quality by the AMSTAR 2 tool and risk of bias by ROBIS. The data will be extracted by three independent reviewers based on a data extraction sheet, which will include the most relevant variables for the analysis and interpretation of the results. The variables will be categorized and described in narrative form or in tables. DISCUSSION: There are some systematic reviews about the use of probiotics to prevent and/or treat dyslipidemia; however, their outcomes related to the ability of probiotics to improve lipid profiles are conflicting. So, an overview on this topic is needed to clarify this important issue. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42017080328.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triglicerídeos / Literatura de Revisão como Assunto / Colesterol / Probióticos / Dislipidemias Tipo de estudo: Clinical_trials / Guideline / Overview / Qualitative_research / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Revista: Syst Rev Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triglicerídeos / Literatura de Revisão como Assunto / Colesterol / Probióticos / Dislipidemias Tipo de estudo: Clinical_trials / Guideline / Overview / Qualitative_research / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Revista: Syst Rev Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido