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Periodontal condition and levels of bacteria associated with periodontitis in individuals with bipolar affective disorders: A case-control study.
Cunha, Fabiano A; Cota, Luís O M; Cortelli, Sheila C; Miranda, Tais B; Neves, Fernando S; Cortelli, José R; Costa, Fernando O.
Afiliação
  • Cunha FA; Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • Cota LOM; Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • Cortelli SC; University of Taubaté, Taubaté, São Paulo, Brazil.
  • Miranda TB; University of Taubaté, Taubaté, São Paulo, Brazil.
  • Neves FS; Federal University of Minas Gerais, Belo Horizonte, Brazil.
  • Cortelli JR; University of Taubaté, Taubaté, São Paulo, Brazil.
  • Costa FO; Federal University of Minas Gerais, Belo Horizonte, Brazil.
J Periodontal Res ; 54(1): 63-72, 2019 Feb.
Article em En | MEDLINE | ID: mdl-30207388
OBJECTIVE: To evaluate the epidemiological and microbiological aspects of the potential association between bipolar affective disorder (BAPD) and periodontitis. METHODOLOGY: The present case-control study comprised 176 individuals with BAPD and 176 controls. All individuals underwent a complete full-mouth periodontal examination and microbiological sampling. Data on bleeding on probing, probing depth, and clinical attachment level in all present teeth were recorded. Quantification of total bacterial load and Aggregatibacter actinomycetemcomitans, Treponema denticola, and Porphyromonas gingivalis counts were performed through qPCR. Data were analyzed using univariate analysis, Spearman correlation and multivariate logistic regression. RESULTS: The prevalence of periodontitis was 39.7% among controls and 58.5% among individuals with BAPD (OR = 2.13; 95% CI 1.39-3.27). A. actinomycetemcomitans and P. gingivalis counts were significantly higher in individuals with BPAD and periodontitis. The final multivariate logistic regression revealed that periodontitis was strongly associated with the total bacterial load (OR = 1.91; 95% IC = 1.0-1.99; P < 0.001) and the depressive phase of BPAD (OR = 28.94; 95% IC = 4.44-177.27; P < 0.001). CONCLUSION: BAPD was associated with increased risk for periodontitis. Individuals with BPAD presented higher levels of A. actinomycetemcomitans and P. gingivalis, suggesting that periodontitis could be a co-morbidity frequently found in individuals with BAPD.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Periodontite / Transtorno Bipolar / Índice Periodontal Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Periodontal Res Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Periodontite / Transtorno Bipolar / Índice Periodontal Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: J Periodontal Res Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos