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Human T Lymphotropic Virus and Pulmonary Diseases.
Dias, Apio R N; Falcão, Luiz F M; Falcão, Aline S C; Normando, Valéria M F; Quaresma, Juarez A S.
Afiliação
  • Dias ARN; Tropical Medicine Center, Federal University of Pará, Belém, Brazil.
  • Falcão LFM; Center of Health and Biological Sciences, State University of Pará, Belém, Brazil.
  • Falcão ASC; Center of Health and Biological Sciences, State University of Pará, Belém, Brazil.
  • Normando VMF; Graduate Program of Virology, Evandro Chagas Institute, Ministry of Health, Ananindeua, Brazil.
  • Quaresma JAS; Graduate Program of Virology, Evandro Chagas Institute, Ministry of Health, Ananindeua, Brazil.
Front Microbiol ; 9: 1879, 2018.
Article em En | MEDLINE | ID: mdl-30154781
Human T lymphotropic virus type 1 (HTLV-1) is the etiological agent of HTLV-1-associated myelopathy, and adult T cell lymphoma/leukemia (ATL/L). Pulmonary complications such as alveolitis and bronchiectasis were found in individuals who develop TSP/HAM due to chronic inflammation. These individuals showed image anomalies in CT scans and changes in pulmonary function parameters distinctive of pulmonary disease. Furthermore, infected individuals have a greater susceptibility to pulmonary tuberculosis either due to changes in the innate immune response, in asymptomatic carriers, or to an opportunistic disease linked to immunodepression, in individuals who develop ATL/L. This summary addresses the general lack of knowledge regarding the relationship between HTLV-1 and pulmonary diseases and provides direction for future work.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Microbiol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Microbiol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Suíça