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Serum Electrolyte Levels and Outcomes in Patients Hospitalized with Hepatic Encephalopathy.
Alsaad, Ali A; Stancampiano, Fernando F; Palmer, William C; Henry, April M; Jackson, Jillian K; Heckman, Michael G; Diehl, Nancy N; Keaveny, Andrew P.
Afiliação
  • Alsaad AA; Department of Internal Medicine, Mayo Clinic, Jacksonville, Florida, USA.
  • Stancampiano FF; Department of Internal Medicine, Mayo Clinic, Jacksonville, Florida, USA.
  • Palmer WC; Department of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, USA.
  • Henry AM; CRISP Program, Mayo Clinic, Jacksonville, Florida, USA.
  • Jackson JK; CRISP Program, Mayo Clinic, Jacksonville, Florida, USA.
  • Heckman MG; Division of Biomedical Statistics and Informatics, Mayo Clinic, Jacksonville, Florida, USA.
  • Diehl NN; Division of Biomedical Statistics and Informatics, Mayo Clinic, Jacksonville, Florida, USA.
Ann Hepatol ; 17(5): 836-842, 2018 Aug 24.
Article em En | MEDLINE | ID: mdl-30145570
INTRODUCTION AND AIMS: Serum electrolyte derangements are common in patients with decompensated cirrhosis hospitalized for hepatic encephalopathy. There are limited data describing the association between electrolyte levels and outcomes in hepatic encephalopathy. We assessed the association between initial serum electrolyte values and outcomes in patients with hepatic encephalopathy. MATERIAL AND METHODS: A total of 385 consecutive patients hospitalized with encephalopathy were included in the study. Baseline electrolyte levels (sodium, potassium, chloride, bicarbonate, calcium and phosphorus) were measured at the time of admission and assessed for association with outcomes, which included survival, admission to the intensive care unit, requirement for mechanical ventilation, and length of hospital stay. P-values ≤ 0.0083 were considered significant after adjustment for multiple testing. RESULTS: In unadjusted analysis, significant associations were identified regarding both bicarbonate and phosphorus (admission to intensive care unit), and calcium (mechanical ventilation); however these findings weakened and no longer approached statistical significance when adjusting for confounding variables. No other significant associations between serum electrolyte measurements and outcomes were observed. CONCLUSIONS: Our findings suggest that in patients hospitalized with encephalopathy, serum electrolyte measurements are not strong predictors of patient outcome.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Admissão do Paciente / Encefalopatia Hepática / Eletrólitos / Cirrose Hepática Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: México
Texto completo
Adicionar na Minha BVS
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Admissão do Paciente / Encefalopatia Hepática / Eletrólitos / Cirrose Hepática Tipo de estudo: Diagnostic_studies / Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Ann Hepatol Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: México