Your browser doesn't support javascript.
loading
Validity and reliability of the Cognitive Complaints in Bipolar Disorder Rating Assessment (COBRA) in Brazilian bipolar patients.
Lima, Flávia M; Cardoso, Taiane A; Serafim, Sílvia D; Martins, Dayane S; Solé, Brisa; Martínez-Arán, Anabel; Vieta, Eduard; Rosa, Adriane R.
Afiliação
  • Lima FM; Laboratório de Psiquiatria Molecular, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
  • Cardoso TA; Programa de Pós-Graduação em Psiquiatria e Ciências do Comportamento, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
  • Serafim SD; Programa de Pós-Graduação em Saúde e Comportamento, Universidade Católica de Pelotas (UCPel), Pelotas, RS, Brazil.
  • Martins DS; Laboratório de Psiquiatria Molecular, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
  • Solé B; Programa de Pós-Graduação em Psiquiatria e Ciências do Comportamento, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.
  • Martínez-Arán A; Laboratório de Psiquiatria Molecular, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.
  • Vieta E; Centro Universitário Ritter dos Reis, Porto Alegre, RS, Brazil.
  • Rosa AR; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Hospital Clinic, Universitat de Barcelona, Barcelona, Catalonia, Spain.
Trends Psychiatry Psychother ; 40(2): 170-178, 2018.
Article em En | MEDLINE | ID: mdl-29995161
INTRODUCTION: In Brazil, there is no valid instrument to measure subjective cognitive dysfunction in bipolar disorder. The present study analyzed the psychometric properties of the Cognitive Complaints in Bipolar Disorder Rating Assessment (COBRA) in Brazilian bipolar patients. We further investigated the relationship between the COBRA, objective cognitive measures, and illness course variables. METHODS: The total sample (N=150) included 85 bipolar disorder patients and 65 healthy controls. The psychometric properties of the COBRA (e.g., internal consistency, concurrent validity, discriminative validity, factor analyses, ROC curve, and feasibility) were analyzed. RESULTS: The COBRA showed a one-factor structure with very high internal consistency (Cronbach's alpha=0.890). Concurrent validity was indicated by a strong correlation with the cognitive domain of the FAST (r=0.811, p<0.001). Bipolar patients experienced greater cognitive complaints (mean=14.69; standard deviation [SD]=10.03) than healthy controls (mean=6.78; SD=5.49; p<0.001), suggesting discriminative validity of the instrument. No significant correlations were found between the COBRA and objective cognitive measures. Furthermore, higher COBRA scores were associated with residual depressive (r=0.448; p<0.001) and manic (r=0.376; p<0.001) symptoms, number of depressive episodes (r=0.306; p=0.011), number of total episodes (r=0.256; p=0.038), and suicide attempts (r=0.356; p=0.003). CONCLUSION: The COBRA is a valid instrument to assess cognitive complaints, and the combined use of subjective-objective cognitive measures enables the correct identification of cognitive dysfunctions in bipolar disorder.
Assuntos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Bipolar / Disfunção Cognitiva / Testes Neuropsicológicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Trends Psychiatry Psychother Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Bipolar / Disfunção Cognitiva / Testes Neuropsicológicos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Female / Humans / Male / Middle aged País/Região como assunto: America do sul / Brasil Idioma: En Revista: Trends Psychiatry Psychother Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil