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Antimicrobial susceptibility of gram-negative bacilli isolated from intra-abdominal and urinary-tract infections in Mexico from 2009 to 2015: Results from the Study for Monitoring Antimicrobial Resistance Trends (SMART).
Ponce-de-Leon, Alfredo; Rodríguez-Noriega, Eduardo; Morfín-Otero, Rayo; Cornejo-Juárez, Dora P; Tinoco, Juan C; Martínez-Gamboa, Areli; Gaona-Tapia, Carmen J; Guerrero-Almeida, M Lourdes; Martin-Onraët, Alexandra; Vallejo Cervantes, José Luis; Sifuentes-Osornio, José.
Afiliação
  • Ponce-de-Leon A; Clinical Microbiology Laboratory, Salvador Zubirán National Institute of Medical Sciences and Nutrition, Mexico City, Mexico.
  • Rodríguez-Noriega E; Department of Infectious Diseases, Salvador Zubirán National Institute of Medical Sciences and Nutrition, Mexico City, Mexico.
  • Morfín-Otero R; Hospital Civil de Guadalajara, Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.
  • Cornejo-Juárez DP; Instituto de Patología Infecciosa y Experimental, Centro Universitario Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico.
  • Tinoco JC; Hospital Civil de Guadalajara, Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.
  • Martínez-Gamboa A; Instituto de Patología Infecciosa y Experimental, Centro Universitario Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico.
  • Gaona-Tapia CJ; Department de Infectious Diseases, National Cancer Institute, Mexico City, Mexico.
  • Guerrero-Almeida ML; Hospital General de Durango, Durango, Mexico.
  • Martin-Onraët A; Clinical Microbiology Laboratory, Salvador Zubirán National Institute of Medical Sciences and Nutrition, Mexico City, Mexico.
  • Vallejo Cervantes JL; Clinical Microbiology Laboratory, Salvador Zubirán National Institute of Medical Sciences and Nutrition, Mexico City, Mexico.
  • Sifuentes-Osornio J; Department of Infectious Diseases, Salvador Zubirán National Institute of Medical Sciences and Nutrition, Mexico City, Mexico.
PLoS One ; 13(6): e0198621, 2018.
Article em En | MEDLINE | ID: mdl-29927958
Antimicrobial resistance is an increasing worldwide concern, which poses unique challenges for the effective prevention and treatment of several infections, especially the ones triggered by organisms producing extended-spectrum ß-lactamases (ESBL). Here, we present the surveillance results of the Study for Monitoring Antimicrobial Resistance Trends (SMART) of Gram-negative bacilli isolated from intra-abdominal infections (IAI, n = 1,235) and urinary-tract infections (UTI, n = 2,682), collected in Mexico from 2009 to 2015. Susceptibility and ESBL status were determined according to the Clinical and Laboratory Standards Institute (CLSI) broth microdilution method. Both E. coli (57%) and K. pneumoniae (12%) were the most frequently reported organisms, as well as the ones with the highest prevalence of ESBL-producing isolates (54% and 39%, respectively). The overall prevalence of ESBL-producing organisms was higher in nosocomial infections than in community-acquired infections (21% vs. 27%). The ESBL rates were 36% for IAI (953/2,682) and 37% for UTI (461/1,235). In addition, ertapenem, imipenem and amikacin were the antibiotics that mostly preserved bacterial susceptibility. Our results show consistency with global trends, although higher than the rates observed in Latin America.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Urinárias / Infecções Intra-Abdominais / Bactérias Gram-Negativas / Anti-Infecciosos Tipo de estudo: Guideline / Risk_factors_studies Limite: Humans País/Região como assunto: Mexico Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Urinárias / Infecções Intra-Abdominais / Bactérias Gram-Negativas / Anti-Infecciosos Tipo de estudo: Guideline / Risk_factors_studies Limite: Humans País/Região como assunto: Mexico Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos