Your browser doesn't support javascript.
loading
Pneumococcal disease burden, clinical presentations and vaccine coverage in the Jamaican population.
Willis, R; Heslop, O; Bodonaik, N; Thame, M; Kumar, U; Aung, M; Kellier, A; Drysdale, S; Leon, V; Smikle, M.
Afiliação
  • Willis R; University Hospital of the West Indies, Kingston, Jamaica.
  • Heslop O; University of Texas Medical Branch, Galveston, TX, USA.
  • Bodonaik N; University Hospital of the West Indies, Kingston, Jamaica.
  • Thame M; University Hospital of the West Indies, Kingston, Jamaica.
  • Kumar U; University Hospital of the West Indies, Kingston, Jamaica.
  • Aung M; National Public Health Laboratory, Kingston, Jamaica.
  • Kellier A; Cornwall Regional Hospital, St. James, Jamaica.
  • Drysdale S; Cornwall Regional Hospital, St. James, Jamaica.
  • Leon V; Jamaica Bustamante Hospital for Children, Kingston, Jamaica.
  • Smikle M; Jamaica Bustamante Hospital for Children, Kingston, Jamaica.
Hum Antibodies ; 26(4): 193-199, 2018.
Article em En | MEDLINE | ID: mdl-29843230
BACKGROUND: Pneumococcal serotypes circulating in any population vary over time and between countries and impacts the effectiveness of pneumococcal vaccination. OBJECTIVE: This study investigated the epidemiology of pneumococcal disease in Jamaica. METHODS: Streptococcus pneumoniae isolates (n= 349) along with demographic and clinical information were collected from patients presenting at the 4 major hospitals in Jamaica over a 2-year period. Serotyping was done using latex agglutination tests and the Quellung reaction assay. RESULTS: Invasive pneumococcal disease (IPD) incidence was 45.4/100,000 in children under 5 yrs and 16.3/100,000 in adults over 65 yrs. Thirteen serogroups were identified among the 120 isolates subjected to grouping; the most common being serogroups: 19 (22/120,18.3%), 6 (20/120,16.7%), 14 (20/120,16.7%), 23 (18/120,15.0%), 3 (11/120,9.2%) and nontypeable (8/120,2.3%). The estimated vaccine coverage rates for the PCV7 and PCV13 vaccines in children less than 5 yrs were 82.5% and 88.7% respectively. The 23-valent PPV23 provided 100% coverage rate in adults over 65 yrs and 82.9% coverage rate for the entire population. CONCLUSIONS: Pneumococcal vaccine coverage rates in Jamaica are comparable to those reported in certain developed countries and higher than in other developing countries. The high incidence of IPD in the paediatric population indicates that routine vaccination would be beneficial.
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Pneumocócicas / Vacinação em Massa Tipo de estudo: Incidence_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male País/Região como assunto: Caribe ingles / Jamaica Idioma: En Revista: Hum Antibodies Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Jamaica País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Pneumocócicas / Vacinação em Massa Tipo de estudo: Incidence_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Aged80 / Child / Child, preschool / Female / Humans / Infant / Male País/Região como assunto: Caribe ingles / Jamaica Idioma: En Revista: Hum Antibodies Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Jamaica País de publicação: Holanda