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Histopathological changes in parotid gland following submandibular gland failure: an experimental animal study.
Yildirim, Yavuz Sultan Selim; Kaygusuz, Irfan; Ozercan, Ibrahim Hanifi; Cetiner, Hasan; Sakallioglu, Oner; Akyigit, Abdulvahap; Duzer, Sertac.
Afiliação
  • Yildirim YSS; Elazig Education and Research Hospital, Department of Otorhinolaryngology, Elazig, Turkey.
  • Kaygusuz I; University of Firat, School of Medicine, Department of Otorhinolaryngology, Elazig, Turkey.
  • Ozercan IH; University of Firat, School of Medicine, Department of Otorhinolaryngology, Elazig, Turkey.
  • Cetiner H; Elazig Education and Research Hospital, Department of Otorhinolaryngology, Elazig, Turkey. Electronic address: cetinerhasan@yahoo.com.
  • Sakallioglu O; Elazig Education and Research Hospital, Department of Otorhinolaryngology, Elazig, Turkey.
  • Akyigit A; Elazig Education and Research Hospital, Department of Otorhinolaryngology, Elazig, Turkey.
  • Duzer S; Elazig Education and Research Hospital, Department of Otorhinolaryngology, Elazig, Turkey.
Braz J Otorhinolaryngol ; 85(4): 422-426, 2019.
Article em En | MEDLINE | ID: mdl-29754976
INTRODUCTION: Submandibular glands are exposed to many effects due to diseases and therapeutic interventions. A study evaluating the effect of submandibular gland dysfunction on the parotid gland has not been presented in the literature. OBJECTIVE: The aim of this study was to evaluate the histopathological changes in the parotid gland following submandibular gland failure. METHODS: Three groups of seven randomly selected female New Zealand rabbits weighing 2500-3000g were studied. Unilateral and bilateral submandibular glands were removed in Groups 1 and 2, respectively. No procedure was performed in Group III, the control group. The parotid glands were removed 30 days later. Histological parameters were evaluated and graded between 0 (none) and 3 (severe). Differences between groups were compared using the Mann-Whitney U test. RESULTS: Mean mucus accumulation in acinar cells was 2.57±0.53 and 1.71±0.75 in Groups 1 and 2, respectively (p<0.05). This value was 0.57±0.53 in Group 3, which was significantly lower than in Groups 1 and 2 (p<0.05). Mean dilatation of the intercalated ducts' lumen was 1.28±0.48 and 1.57±0.53 in Groups 1 and 2, respectively (p>0.05). This value was 0.28±0.48 in Group 3, which was significantly lower than in Groups 1 and 2 (p<0.05). Mean mucus accumulation in the intercalated ducts' lumen was 2.00±0.81 and 1.00±0.57 in Groups 2 and 3, respectively (p<0.05). CONCLUSION: The findings of this study indicate that only 1 month after submandibular gland failure, the parotid glands exhibit significant changes.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glândula Parótida / Glândula Submandibular Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Braz J Otorhinolaryngol Assunto da revista: OTORRINOLARINGOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Turquia País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glândula Parótida / Glândula Submandibular Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Braz J Otorhinolaryngol Assunto da revista: OTORRINOLARINGOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Turquia País de publicação: Brasil