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Trabecular Bone Score Is a Valuable Addition to Bone Mineral Density for Bone Quality Assessment in Older Mexican American Women With Type 2 Diabetes.
Rianon, Nahid; Ambrose, Catherine G; Buni, Maryam; Watt, Gordon; Reyes-Ortiz, Carlos; Lee, Miryoung; McCormick, Joseph; Fisher-Hoch, Susan.
Afiliação
  • Rianon N; Department of Internal Medicine/Geriatric and Palliative Medicine, McGovern Medical School, part of UTHealth, Houston, TX, USA. Electronic address: nahid.j.rianon@uth.tmc.edu.
  • Ambrose CG; Department of Orthopedic Surgery, McGovern Medical School, part of UTHealth, Houston, TX, USA.
  • Buni M; Department of Internal Medicine/Rheumatology, McGovern Medical School, part of UTHealth, Houston, TX, USA.
  • Watt G; Department of Epidemiology, Human Genetics and Environmental Sciences, UTSPH, Brownsville Campus, Brownsville, TX, USA.
  • Reyes-Ortiz C; Department of Internal Medicine/Geriatric and Palliative Medicine, McGovern Medical School, part of UTHealth, Houston, TX, USA.
  • Lee M; Department of Epidemiology, Human Genetics and Environmental Sciences, UTSPH, Brownsville Campus, Brownsville, TX, USA.
  • McCormick J; Department of Epidemiology, Human Genetics and Environmental Sciences, UTSPH, Brownsville Campus, Brownsville, TX, USA.
  • Fisher-Hoch S; Department of Epidemiology, Human Genetics and Environmental Sciences, UTSPH, Brownsville Campus, Brownsville, TX, USA.
J Clin Densitom ; 21(3): 355-359, 2018.
Article em En | MEDLINE | ID: mdl-29685494
Altered bone quality due to the underlying metabolic changes of type 2 diabetes (T2D) has been hypothesized to affect bone strength, leading to increased fracture risk in patients with T2D. Lumbar spine trabecular bone score (LS-TBS), an indirect measure of trabecular microarchitecture, provides information on bone quality and has been associated with T2D. However, trabecular bone score (TBS) is also affected by demographic patterns and body size, and is expected to be different in people from various ethnic or racial backgrounds. Therefore, it is important to understand associations between T2D and TBS for each ethnic or racial group separately. Although the relationship between TBS and age has been reported to be similar between non-Hispanic Caucasians and Mexican Americans (MAs), data on associations of LS-TBS with T2D in older MAs are lacking. Here, we report associations between TBS and T2D in 149 older MA men and women. Participants are part of a cohort known as the Cameron County Hispanic Cohort in Texas who have high prevalence of obesity and poor glycemic control. Bone mineral density was not altered for MA women with T2D, but was significantly higher in MA men with T2D compared with MA men without diabetes. Low LS-TBS was associated with T2D in women in our study. Although low TBS was associated with older age in men, TBS did not show any significant association with T2D for men. These results are similar to those found in other studies of non-Hispanic whites with diabetes. LS-TBS may add value in diagnosing poor bone quality in older MA women with T2D regardless of bone mineral density scoring.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Densidade Óssea / Diabetes Mellitus Tipo 2 / Osso Esponjoso Tipo de estudo: Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Mexico Idioma: En Revista: J Clin Densitom Assunto da revista: ORTOPEDIA Ano de publicação: 2018 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Densidade Óssea / Diabetes Mellitus Tipo 2 / Osso Esponjoso Tipo de estudo: Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged País/Região como assunto: Mexico Idioma: En Revista: J Clin Densitom Assunto da revista: ORTOPEDIA Ano de publicação: 2018 Tipo de documento: Article País de publicação: Estados Unidos