Your browser doesn't support javascript.
loading
Burden of Influenza in Less Than 5-Year-Old Children Admitted to Hospital with Pneumonia in Developing and Emerging Countries: A Descriptive, Multicenter Study.
Dananché, Cédric; Sánchez Picot, Valentina; Bénet, Thomas; Messaoudi, Mélina; Chou, Monidarin; Wang, Jianwei; Pape, Jean-William; Awasthi, Shally; Bavdekar, Ashish; Rakoto-Andrianarivelo, Mala; Sylla, Mariam; Nymadawa, Pagbajabyn; Russomando, Graciela; Komurian-Pradel, Florence; Endtz, Hubert; Paranhos-Baccalà, Gláucia; Vanhems, Philippe.
Afiliação
  • Dananché C; Infection Control and Epidemiology Department, Hospices Civils de Lyon, Lyon, France.
  • Sánchez Picot V; Emerging Pathogens Laboratory, Fondation Mérieux, Centre International de Recherche en Infectiologie, INSERM U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France.
  • Bénet T; Emerging Pathogens Laboratory, Fondation Mérieux, Centre International de Recherche en Infectiologie, INSERM U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France.
  • Messaoudi M; Infection Control and Epidemiology Department, Hospices Civils de Lyon, Lyon, France.
  • Chou M; Emerging Pathogens Laboratory, Fondation Mérieux, Centre International de Recherche en Infectiologie, INSERM U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France.
  • Wang J; Emerging Pathogens Laboratory, Fondation Mérieux, Centre International de Recherche en Infectiologie, INSERM U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France.
  • Pape JW; Faculty of Pharmacy, University of Health Sciences, Phnom Penh, Cambodia.
  • Awasthi S; MOH Key Laboratory of the Systems Biology of Pathogens and Dr. Christophe Mérieux Laboratory, Fondation Mérieux, Institute of Pathogen Biology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Bavdekar A; Centres GHESKIO (Groupe Haïtien d'Etude du Sarcome de Kaposi et des Infections Opportunistes), Port-au-Prince, Haiti.
  • Rakoto-Andrianarivelo M; Chatrapati Shahu Ji Maharaj Medical University, Lucknow, India.
  • Sylla M; KEM Hospital Research Center, Pune, India.
  • Nymadawa P; Fondation Mérieux, Centre d'Infectiologie Charles Mérieux, Antananarivo, Madagascar.
  • Russomando G; Gabriel Touré Hospital, Bamako, Mali.
  • Komurian-Pradel F; Mongolian Academy of Medical Sciences, Ulaanbaatar, Mongolia.
  • Endtz H; Research Institute of Health, Asunción, Paraguay.
  • Paranhos-Baccalà G; Emerging Pathogens Laboratory, Fondation Mérieux, Centre International de Recherche en Infectiologie, INSERM U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France.
  • Vanhems P; Department of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands.
  • For The Gabriel Network; Emerging Pathogens Laboratory, Fondation Mérieux, Centre International de Recherche en Infectiologie, INSERM U1111, CNRS UMR5308, ENS de Lyon, UCBL1, Lyon, France.
Am J Trop Med Hyg ; 98(6): 1805-1810, 2018 06.
Article em En | MEDLINE | ID: mdl-29663903
This descriptive 4-year study reports the proportion of detection of influenza viruses in less than 5-year-old children hospitalized for pneumonia in eight developing and emerging countries and describes clinical and microbiological characteristics of influenza-related pneumonia cases. Hospitalized children presenting radiologically confirmed pneumonia aged 2-60 months were prospectively enrolled in this observational standardized study. Mean proportion of isolated influenza virus was 9.7% (95% confidence interval: 7.9-11.8%) among 888 pneumonia children analyzed, with moderate heterogeneity between countries-ranging from 6.2% in Cambodia to 18.8% in Haiti. The clinical characteristics of children with influenza-related pneumonia were not substantially different from those of other pneumonia cases. Influenza A H1N1-related pneumonia cases appeared as more severe than pneumonia cases related to other strains of influenza. Streptococcus pneumoniae was detected more often in blood samples from influenza-related cases than in those without detected influenza viruses (19.7% versus 9.5%, P = 0.018). Influenza-related pneumonia is frequent among children less than 5 years old with pneumonia, living in developing and emerging countries. Influenza might be a frequent etiologic agent responsible for pneumonia or a predisposing status factor for pneumococcal-related pneumonia in this population.
Assuntos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia / Streptococcus / Influenza Humana / Vírus da Influenza A Subtipo H1N1 Tipo de estudo: Clinical_trials / Observational_studies / Risk_factors_studies Limite: Child, preschool / Female / Humans / Infant / Male País/Região como assunto: Asia / Caribe / Haiti Idioma: En Revista: Am J Trop Med Hyg Ano de publicação: 2018 Tipo de documento: Article País de afiliação: França País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia / Streptococcus / Influenza Humana / Vírus da Influenza A Subtipo H1N1 Tipo de estudo: Clinical_trials / Observational_studies / Risk_factors_studies Limite: Child, preschool / Female / Humans / Infant / Male País/Região como assunto: Asia / Caribe / Haiti Idioma: En Revista: Am J Trop Med Hyg Ano de publicação: 2018 Tipo de documento: Article País de afiliação: França País de publicação: Estados Unidos