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Rural distribution of human papilloma virus in low- and middle-income countries.
Atkinson, Aaron; Studwell, Courtney; Bejarano, Suyapa; Castellón, Ana Marcela Zapata; Espinal, Jorge Arturo Plata; Deharvengt, Sophie; LaRochelle, Ethan P M; Kennedy, Linda S; Tsongalis, Gregory J.
Afiliação
  • Atkinson A; Department of Pathology and Laboratory Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA.
  • Studwell C; University of Connecticut, Diagnostic Genetic Sciences Program, Storrs, CT, USA.
  • Bejarano S; Liga Contra el Cáncer, San Pedro Sula, Honduras.
  • Castellón AMZ; Liga Contra el Cáncer, San Pedro Sula, Honduras.
  • Espinal JAP; Liga Contra el Cáncer, San Pedro Sula, Honduras.
  • Deharvengt S; Department of Pathology and Laboratory Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA.
  • LaRochelle EPM; Thayer School of Engineering, Dartmouth College, Hanover, NH, USA.
  • Kennedy LS; Norris Cotton Cancer Center, Lebanon, NH, USA; Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
  • Tsongalis GJ; Department of Pathology and Laboratory Medicine, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA; Norris Cotton Cancer Center, Lebanon, NH, USA; Geisel School of Medicine at Dartmouth, Hanover, NH, USA. Electronic address: Gregory.j.tsongalis@hitchcock.org.
Exp Mol Pathol ; 104(2): 146-150, 2018 04.
Article em En | MEDLINE | ID: mdl-29551573
Cervical cancer rates in low- and middle-income countries (LMICs) are higher than in developed countries and account for 80% of an estimated 500,000 new cases annually. Factors that contribute to this are that diagnostic and prevention strategies designed for developed countries suffer from the combination of low vaccination rates and limitations due to lack of consistent access to both healthcare and supplies. Here we: 1) improve upon our LMIC deployable HPV test and 2) determine both the high and low-risk HPV genotype prevalence in an isolated Honduran population. We found an unexpected HPV distribution with an abundance of HPV 52 and HPV 72 infections. In this context, molecular testing using a LMIC deployable approach for the detection of HPV can aid in both the triage of HPV positive cytology-based follow up and provide information regarding HPV genotype distribution in support of vaccination strategies.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Papillomaviridae / Virologia / Infecções por Papillomavirus Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Female / Humans País/Região como assunto: America central / Honduras Idioma: En Revista: Exp Mol Pathol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Papillomaviridae / Virologia / Infecções por Papillomavirus Tipo de estudo: Prevalence_studies / Risk_factors_studies Limite: Female / Humans País/Região como assunto: America central / Honduras Idioma: En Revista: Exp Mol Pathol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Holanda