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Maternal soybean diet during lactation alters breast milk composition and programs the lipid profile in adult male rat offspring.
Vieira, Adriana Moura; de Almeida Brasiel, Poliana Guiomar; Ferreira, Maíra Schuchter; Mateus, Kacia; Figueiredo, Mariana Sarto; Lisboa, Patrícia Cristina; de Moura, Egberto Gaspar; do Amaral Corrêa, José Otavio; Lopes, Fernando Cesar Ferraz; da Silva, Paulo Henrique Fonseca; Sabarense, Céphora Maria; Dutra, Sheila Cristina Potente Luquetti; de Aguiar, Aline Silva.
Afiliação
  • Vieira AM; Department of Nutrition, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
  • de Almeida Brasiel PG; Department of Nutrition, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
  • Ferreira MS; Department of Nutrition, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
  • Mateus K; Department of Nutrition, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
  • Figueiredo MS; Department of Physiological Sciences, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Lisboa PC; Department of Physiological Sciences, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • de Moura EG; Department of Physiological Sciences, State University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • do Amaral Corrêa JO; Department of Pharmaceutical Sciences, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
  • Lopes FCF; Embrapa Dairy Cattle of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
  • da Silva PHF; Department of Nutrition, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
  • Dutra SCPL; Department of Nutrition, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil. sheila.dutra@ufjf.edu.br.
  • de Aguiar AS; Department of Nutrition, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil.
Endocrine ; 60(2): 272-281, 2018 05.
Article em En | MEDLINE | ID: mdl-29520624
PURPOSE: To evaluate the effects of maternal dietary soybean during lactation on the milk composition, body composition, lipid profile and glucose homeostasis of dams and offspring at weaning (21 days) and adulthood (150 days). METHODS: Lactating rats were divided into: casein control (C): casein diet; soy (S): soybean diet; soy oil control (SOC): casein diet, but with fat content similar to the S group. RESULTS: At 21 days, S mothers showed lower estradiol, total cholesterol (TC), low-density lipoprotein cholesterol (LDL) and triglycerides (TG) in serum; and lower TC and TG in milk. The S offspring had lower body weight, body fat mass, TC, LDL, hyperleptinemia and hypertriglyceridemia. At 150 days, S offspring presented higher total mineral content and lower TC (v. SOC) and LDL (v. C and SOC), and hyperinsulinemia with lower glycemia v. SOC group, which had lower insulinemia with higher glycemia, TC and LDL. CONCLUSIONS: Maternal intake of soybeans in lactation changes the lipid content of breast milk and programmed offspring for phenotype of the lower metabolic risk, with lower serum TC and LDL, and seems to protect the progeny of alterations in glucose metabolism despite the higher lipid content. The difference in fat content of breast milk and the higher isoflavones content of soy diet are possible imprinting factors that could program the offspring.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Composição Corporal / Lactação / Exposição Materna / Alimentos de Soja / Leite Limite: Animals / Pregnancy Idioma: En Revista: Endocrine Assunto da revista: ENDOCRINOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Composição Corporal / Lactação / Exposição Materna / Alimentos de Soja / Leite Limite: Animals / Pregnancy Idioma: En Revista: Endocrine Assunto da revista: ENDOCRINOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos