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Economic assessment of postoperative pain control strategies for treatment of adult patients with cancer.
Santos, Rafael Freitas Dos; Bliacheriene, Fernando; Sarti, Flavia Mori.
Afiliação
  • Santos RFD; Pharmacy degree from Universidade de São Paulo (USP), São Paulo, SP, Brazil.
  • Bliacheriene F; MD, PhD in Medicine from Faculdade de Medicina da USP (FMUSP), São Paulo, SP, Brazil.
  • Sarti FM; Economist and Nutritionist, PhD in Applied Human Nutrition from USP, São Paulo, SP, Brazil.
Rev Assoc Med Bras (1992) ; 63(11): 962-970, 2017 Nov.
Article em En | MEDLINE | ID: mdl-29451660
OBJECTIVE: The authors performed an economic assessment of opioids currently being used for control of postoperative pain relating to the surgical treatment of cancer (fentanyl and sufentanil) within the Brazilian Unified Health System (SUS, in the Portuguese acronym). METHOD: The assessment was based on the perspective of the government, in order to collaborate with the promotion of effectiveness in public policies of health, and to optimize the allocation of public resources into health. A cost-effectiveness analysis was performed using data collected from the Brazilian Unified Health System and information from literature review, in order to build a decision tree on the alternatives for control of postoperative pain related to cancer treatment among adult patients. The outcomes considered were: effectiveness of postoperative analgesia and occurrence of nausea and vomit in the 48 hour period after surgery, and additional 24-hour cycles in patient follow-up. A univariate sensitivity analysis was conducted in order to verify robustness of the model estimated. RESULTS: Literature review showed a limited number of studies directly comparing fentanyl and sufentanil for control of postoperative pain. The adoption of sufentanil (cost = U$ 25.72 / outcome = 1.6 VAS points) was dominant in relation to the use of fentanyl (cost = U$ 32.58 / outcome = 2.6 VAS points). The estimated model showed robustness in relation to changes in the parameters analyzed. CONCLUSION: Sufentanil presented higher cost-effectiveness ratio in relation to fentanyl for control of postoperative pain in surgeries related to cancer treatment among adult patients in the Brazilian Unified Health System.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor Pós-Operatória / Fentanila / Sufentanil / Analgésicos Opioides / Neoplasias Tipo de estudo: Health_economic_evaluation / Prognostic_studies Limite: Adult / Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Rev Assoc Med Bras (1992) Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor Pós-Operatória / Fentanila / Sufentanil / Analgésicos Opioides / Neoplasias Tipo de estudo: Health_economic_evaluation / Prognostic_studies Limite: Adult / Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Rev Assoc Med Bras (1992) Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil