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Mediators of episodic memory decay across the adult life span.
Cansino, Selene; Torres-Trejo, Frine; Estrada-Manilla, Cinthya; Hernández-Ramos, Evelia; Martínez-Galindo, Joyce Graciela; Gómez-Fernández, Tania; Ayala-Hernández, Mariana; Ramírez-González, María Dolores; Ruiz-Velasco, Silvia.
Afiliação
  • Cansino S; Laboratory of NeuroCognition, Faculty of Psychology, National Autonomous University of Mexico, Mexico City, 04510, Mexico. selene@unam.mx.
  • Torres-Trejo F; Laboratory of NeuroCognition, Faculty of Psychology, National Autonomous University of Mexico, Mexico City, 04510, Mexico.
  • Estrada-Manilla C; Laboratory of NeuroCognition, Faculty of Psychology, National Autonomous University of Mexico, Mexico City, 04510, Mexico.
  • Hernández-Ramos E; Laboratory of NeuroCognition, Faculty of Psychology, National Autonomous University of Mexico, Mexico City, 04510, Mexico.
  • Martínez-Galindo JG; Laboratory of NeuroCognition, Faculty of Psychology, National Autonomous University of Mexico, Mexico City, 04510, Mexico.
  • Gómez-Fernández T; Laboratory of NeuroCognition, Faculty of Psychology, National Autonomous University of Mexico, Mexico City, 04510, Mexico.
  • Ayala-Hernández M; Laboratory of NeuroCognition, Faculty of Psychology, National Autonomous University of Mexico, Mexico City, 04510, Mexico.
  • Ramírez-González MD; Department of Pharmacology, School of Medicine, National Autonomous University of Mexico, Mexico City, 04510, Mexico.
  • Ruiz-Velasco S; Applied Mathematics and Systems Research Institute, National Autonomous University of Mexico, Mexico City, 04510, Mexico.
Sci Rep ; 8(1): 2610, 2018 02 08.
Article em En | MEDLINE | ID: mdl-29422554
The ability to remember the details of our own experiences declines gradually as we get old. The reason for this decay has been attributed to several factors besides age, such as education, nutrient intake and health status. However, the influence of these factors has mainly been examined individually and rarely together. Here we identify those factors that jointly act as mediators of episodic memory decay across the adult life span. We examined source memory in a lifespan sample of 1557 healthy adults. A total of 70 physical, biological and lifestyle variables were measured and introduced into a structural equation model as potential mediators that intervene between age and source memory. Only 14 mediator variables reliably mediated source memory decay; notably, eight of these variables have an effect on the cardiovascular system. The model unequivocally highlights that the mediators that may impair cardiovascular functioning also impact brain resources involved in episodic memory. We identified the factors that are relevant to episodic memory decline when they interact together as occurs in real life.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Memória Episódica / Envelhecimento Cognitivo / Estilo de Vida / Transtornos da Memória Tipo de estudo: Prognostic_studies Aspecto: Patient_preference Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: Mexico Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: México País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Memória Episódica / Envelhecimento Cognitivo / Estilo de Vida / Transtornos da Memória Tipo de estudo: Prognostic_studies Aspecto: Patient_preference Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: Mexico Idioma: En Revista: Sci Rep Ano de publicação: 2018 Tipo de documento: Article País de afiliação: México País de publicação: Reino Unido