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Relationship Between Brain-Derived Neurotrofic Factor (Bdnf) and Sleep on Depression: A Critical Review.
Monteiro, Bárbara C; Monteiro, Suzana; Candida, Maristela; Adler, Nathalia; Paes, Flavia; Rocha, Nuno; Nardi, Antonio Egidio; Murillo-Rodriguez, Eric; Machado, Sergio.
Afiliação
  • Monteiro BC; Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Monteiro S; Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Candida M; Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Adler N; Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Paes F; Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Rocha N; Polytechnic Institute of Porto, Health School, , Portugal.
  • Nardi AE; Intercontinental Neuroscience Research Group, Brazil.
  • Murillo-Rodriguez E; Laboratory of Panic and Respiration, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
  • Machado S; Laboratorio de Neurociencias Moleculares e Integrativas, Escuela de Medicina, División Ciencias de la Salud, Universidad Anáhuac Mayab, Merida, Mexico.
Article em En | MEDLINE | ID: mdl-29299044
The Brain-Derived Neurotrofic Factor (BDNF) is one of the most important neurotrophins in the brain and it is suggested influences the activity of the serotonergic, noradrenergic and dopaminergic pathways. In the last few years, it has been hypothesized that BDNF level is related with depression and sleep. Several studies show that depressive subjects present low levels of BDNF in the brain. Poor sleep quality is also related with alterations in the BDNF concentration. Some authors argue that most of the cases show that impaired sleep quality increases the stress and, consequently, the vulnerability to depressive disorders, suggesting that there is a relationship between sleep, depression and BDNF levels.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Clin Pract Epidemiol Ment Health Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Emirados Árabes Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Clin Pract Epidemiol Ment Health Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Emirados Árabes Unidos