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Effects of Herpes Simplex Virus Infections on Seminal Parameters in Male Partners of Infertile Couples.
Kurscheidt, Fábio A; Damke, Edilson; Bento, Jaqueline C; Balani, Valério A; Takeda, Karen I; Piva, Sérgio; Piva, João P; Irie, Mary M T; Gimenes, Fabrícia; Consolaro, Marcia E L.
Afiliação
  • Kurscheidt FA; Programa de Pós-Graduação em Biociências e Fisiopatologia, Departamento de Análises Clínicas e Biomedicina, Universidade Estadual de Maringá (UEM), Maringá, Paraná, Brazil; Sperm Analysis Section, São Camilo Laboratory, Maringá, Paraná, Brazil.
  • Damke E; Programa de Pós-Graduação em Biociências e Fisiopatologia, Departamento de Análises Clínicas e Biomedicina, Universidade Estadual de Maringá (UEM), Maringá, Paraná, Brazil.
  • Bento JC; Sperm Analysis Section, São Camilo Laboratory, Maringá, Paraná, Brazil.
  • Balani VA; Sperm Analysis Section, São Camilo Laboratory, Maringá, Paraná, Brazil.
  • Takeda KI; Sperm Analysis Section, São Camilo Laboratory, Maringá, Paraná, Brazil.
  • Piva S; Sperm Analysis Section, São Camilo Laboratory, Maringá, Paraná, Brazil.
  • Piva JP; Sperm Analysis Section, São Camilo Laboratory, Maringá, Paraná, Brazil.
  • Irie MMT; Programa de Pós-Graduação em Biociências e Fisiopatologia, Departamento de Análises Clínicas e Biomedicina, Universidade Estadual de Maringá (UEM), Maringá, Paraná, Brazil.
  • Gimenes F; Programa de Pós-Graduação em Biociências e Fisiopatologia, Departamento de Análises Clínicas e Biomedicina, Universidade Estadual de Maringá (UEM), Maringá, Paraná, Brazil.
  • Consolaro MEL; Programa de Pós-Graduação em Biociências e Fisiopatologia, Departamento de Análises Clínicas e Biomedicina, Universidade Estadual de Maringá (UEM), Maringá, Paraná, Brazil. Electronic address: melconsolaro@gmail.com.
Urology ; 113: 52-58, 2018 Mar.
Article em En | MEDLINE | ID: mdl-29287977
OBJECTIVE: To assess the possibility that herpes simplex virus (HSV) infection could affect seminal parameters, we (1) standardize and validate a multiplex polymerase chain reaction (M-PCR) assay to detect HSV-1 and HSV-2 in semen, and (2) determine the prevalence of HSV-1/-2 in the semen of randomized male partners of couples seeking fertility evaluation. MATERIALS AND METHODS: A total of 279 semen samples were included in the study from men who visited the Sperm Analysis Section of São Camilo Laboratory of Maringá, Brazil, between November 2014 and July 2015. Eligible men were 18 years or older and had a semen analysis due fertility evaluation (after failing to conceive with their partner after 1 year of unprotected intercourse). Basic seminal parameters were analyzed, and HSV-1 and HSV-2 were detected by M-PCR. RESULTS: The M-PCR assay clearly distinguished and identified 2 HSV types in semen samples. HSV in total was detected in 10.7% of samples, of which 7.5% had HSV-1 exclusively and 3.2% had HSV-2 exclusively. We detected a significant association of HSV-2 infection with hematospermia and with a lower mean seminal volume, and between HSV-1 infection and a lower mean sperm count. CONCLUSION: These findings suggest that the male partners of infertile couples with HSV infections may have changes on the 2 equally important components of semen, spermatozoa and seminal fluid, which may influence fertility. Further studies enrolling a larger number of patients are necessary to confirm these data and to elucidate the clinical relevance of HSV presence in semen.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sêmen / Motilidade dos Espermatozoides / Herpes Simples / Infertilidade Masculina Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Humans / Male / Middle aged Idioma: En Revista: Urology Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sêmen / Motilidade dos Espermatozoides / Herpes Simples / Infertilidade Masculina Tipo de estudo: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Humans / Male / Middle aged Idioma: En Revista: Urology Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos