Your browser doesn't support javascript.
loading
Development of an in vitro mechanical gastric system (IMGS) with realistic peristalsis to assess lipid digestibility.
Barros, Lorena; Retamal, Christian; Torres, Héctor; Zúñiga, Rommy N; Troncoso, Elizabeth.
Afiliação
  • Barros L; Department of Chemistry, Universidad Tecnológica Metropolitana, Las Palmeras 3360, Ñuñoa, Santiago, Chile.
  • Retamal C; Department of Chemistry, Universidad Tecnológica Metropolitana, Las Palmeras 3360, Ñuñoa, Santiago, Chile.
  • Torres H; Programa Prospectiva e Innovación Tecnológica, Universidad Tecnológica Metropolitana, Dieciocho 414, Santiago, Chile.
  • Zúñiga RN; Department of Biotechnology, Universidad Tecnológica Metropolitana, Las Palmeras 3360, Ñuñoa, Santiago, Chile.
  • Troncoso E; Department of Chemistry, Universidad Tecnológica Metropolitana, Las Palmeras 3360, Ñuñoa, Santiago, Chile; Programa Institucional de Fomento a la Investigación, Desarrollo e Innovación, Universidad Tecnológica Metropolitana, Ignacio Valdivieso 2409, San Joaquín, Santiago, Chile. Electronic address:
Food Res Int ; 90: 216-225, 2016 Dec.
Article em En | MEDLINE | ID: mdl-29195874
A new in vitro mechanical gastric system (IMGS) was fabricated which incorporates: a J-shaped stomach, a mechanical system with realistic peristaltic frequency and force magnitude, and a reproduction of the gastric pH curve. To evaluate the impact of a more realistic gastric peristalsis on the intestinal lipolysis of protein-stabilized O/W emulsions, the emulsions were subjected to two different in vitro digestion methodologies: (i) gastric digestion in the IMGS and intestinal digestion in a stirred beaker (SB), and (ii) gastric and intestinal digestion assays carried out in SBs. At the end of the intestinal digestion, the total amount of free fatty acids released was significantly higher for the first methodology (IMGS-SB) in comparison with the second one (27.5% vs. 23.0%), probably due to the higher physical instability induced by the IMGS in the gastric contents. These results reaffirm that O/W emulsion stability plays a crucial role in controlling the final extent of lipolysis of this kind of food-grade emulsions.
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Food Res Int Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Chile País de publicação: Canadá

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Food Res Int Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Chile País de publicação: Canadá