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A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family.
Carreras-Puigvert, Jordi; Zitnik, Marinka; Jemth, Ann-Sofie; Carter, Megan; Unterlass, Judith E; Hallström, Björn; Loseva, Olga; Karem, Zhir; Calderón-Montaño, José Manuel; Lindskog, Cecilia; Edqvist, Per-Henrik; Matuszewski, Damian J; Ait Blal, Hammou; Berntsson, Ronnie P A; Häggblad, Maria; Martens, Ulf; Studham, Matthew; Lundgren, Bo; Wählby, Carolina; Sonnhammer, Erik L L; Lundberg, Emma; Stenmark, Pål; Zupan, Blaz; Helleday, Thomas.
Afiliação
  • Carreras-Puigvert J; Division of Translational Medicine and Chemical Biology, Science for Life Laboratory, Department of Molecular Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 171 65, Sweden. jordi.carreras.puigvert@scilifelab.se.
  • Zitnik M; Faculty of Computer and Information Science, University of Ljubljana, SI-1000, Ljubljana, Slovenia.
  • Jemth AS; Department of Computer Science, Stanford University, Palo Alto, CA, 94305, USA.
  • Carter M; Division of Translational Medicine and Chemical Biology, Science for Life Laboratory, Department of Molecular Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 171 65, Sweden.
  • Unterlass JE; Department of Biochemistry and Biophysics, Stockholm University, 106 91, Stockholm, Sweden.
  • Hallström B; Division of Translational Medicine and Chemical Biology, Science for Life Laboratory, Department of Molecular Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 171 65, Sweden.
  • Loseva O; Cell Profiling-Affinity Proteomics, Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, 17165, Sweden.
  • Karem Z; Division of Translational Medicine and Chemical Biology, Science for Life Laboratory, Department of Molecular Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 171 65, Sweden.
  • Calderón-Montaño JM; Division of Translational Medicine and Chemical Biology, Science for Life Laboratory, Department of Molecular Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 171 65, Sweden.
  • Lindskog C; Division of Translational Medicine and Chemical Biology, Science for Life Laboratory, Department of Molecular Biochemistry and Biophysics, Karolinska Institutet, Stockholm, 171 65, Sweden.
  • Edqvist PH; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, 751 85, Uppsala, Sweden.
  • Matuszewski DJ; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, 751 85, Uppsala, Sweden.
  • Ait Blal H; Centre for Image Analysis and Science for Life Laboratory, Uppsala University, Uppsala, 751 05, Sweden.
  • Berntsson RPA; Cell Profiling-Affinity Proteomics, Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, 17165, Sweden.
  • Häggblad M; Department of Biochemistry and Biophysics, Stockholm University, 106 91, Stockholm, Sweden.
  • Martens U; Biochemical and Cellular Screening Facility, Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Stockholm, 171 65, Sweden.
  • Studham M; Biochemical and Cellular Screening Facility, Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Stockholm, 171 65, Sweden.
  • Lundgren B; Stockholm Bioinformatics Center, Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Box 1031, 171 21, Solna, Sweden.
  • Wählby C; Biochemical and Cellular Screening Facility, Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Stockholm, 171 65, Sweden.
  • Sonnhammer ELL; Centre for Image Analysis and Science for Life Laboratory, Uppsala University, Uppsala, 751 05, Sweden.
  • Lundberg E; Stockholm Bioinformatics Center, Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Box 1031, 171 21, Solna, Sweden.
  • Stenmark P; Cell Profiling-Affinity Proteomics, Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, 17165, Sweden.
  • Zupan B; Department of Biochemistry and Biophysics, Stockholm University, 106 91, Stockholm, Sweden.
  • Helleday T; Faculty of Computer and Information Science, University of Ljubljana, SI-1000, Ljubljana, Slovenia.
Nat Commun ; 8(1): 1541, 2017 11 16.
Article em En | MEDLINE | ID: mdl-29142246

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirofosfatases / Família Multigênica / Perfilação da Expressão Gênica / Redes Reguladoras de Genes Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suécia País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirofosfatases / Família Multigênica / Perfilação da Expressão Gênica / Redes Reguladoras de Genes Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Suécia País de publicação: Reino Unido