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Dipteryx alata Vogel May Improve Lipid Profile and Atherogenic Indices in Wistar Rats Dipteryx alata and Atherogenic Indices.
Ragassi Fiorini, Adriana Maria; Barbalho, Sandra Maria; Guiguer, Élen Landgraf; Oshiiwa, Marie; Mendes, Claudemir Gregório; Vieites, Rogério Lopes; Chies, Agnaldo Bruno; de Oliveira, Priscilla Bianca; de Souza, Maricelma da Silva Soares; Nicolau, Claudia Cristina T.
Afiliação
  • Ragassi Fiorini AM; 1 Department of Biochemistry and Nutrition, Faculty of Food Technology of Marília , Marília, SP, Brazil .
  • Barbalho SM; 1 Department of Biochemistry and Nutrition, Faculty of Food Technology of Marília , Marília, SP, Brazil .
  • Guiguer ÉL; 2 Department of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR) , Marília, SP, Brazil .
  • Oshiiwa M; 1 Department of Biochemistry and Nutrition, Faculty of Food Technology of Marília , Marília, SP, Brazil .
  • Mendes CG; 2 Department of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR) , Marília, SP, Brazil .
  • Vieites RL; 1 Department of Biochemistry and Nutrition, Faculty of Food Technology of Marília , Marília, SP, Brazil .
  • Chies AB; 2 Department of Biochemistry and Pharmacology, School of Medicine, University of Marília (UNIMAR) , Marília, SP, Brazil .
  • de Oliveira PB; 3 Faculty of Agronomic Sciences, University Estadual Paulista-UNESP , Botucatu, SP, Brazil .
  • de Souza MDSS; 4 Department of Pharmacology, Marilia Faculty of Medicine, FAMEMA , Marília, SP, Brazil .
  • Nicolau CCT; 4 Department of Pharmacology, Marilia Faculty of Medicine, FAMEMA , Marília, SP, Brazil .
J Med Food ; 20(11): 1121-1126, 2017 Nov.
Article em En | MEDLINE | ID: mdl-29072970
Worldwide prevalence of noncommunicable chronic degenerative diseases is among the main causes of death worldwide. The consumption of some foods such as nuts and seeds may be beneficial in preventing these diseases. Dipteryx alata Vogel (DA), known popularly as Baru, belongs to the family Fabaceae and is a native fruit tree from the Brazilian savanna. The purpose of this study was to evaluate the use of seeds of DA on the metabolic and oxidative profile of Wistar rats. Animals were divided randomly into four groups (n = 10): G1 (control group), and G2 (treated with DA 20%), G3 (treated with DA 30%), and G4 (treated with DA 40%). After 40 days, animals were euthanized and metabolic and oxidative profiles were analyzed (glycemia, cholesterol, triglycerides [TGs], high-density lipoprotein-cholesterol [HDL-c], very low-density lipoprotein-cholesterol [VLDL-c], low-density lipoprotein-cholesterol [LDL-c], C reactive protein, aspartate aminotransferase, alanine aminotransferase, Lee index, weight, visceral fat, ferric reducing ability of plasma, and ferric-xylenol orange method. The use of the seeds was effective in reducing TGs, VLDL-c, LDL-c, and increasing HDL-c but did not interfere in the percentage of weight gain, visceral fat, levels of total cholesterol, and oxidative stress. Based on our results, it is possible to say that the use of DA may improve the lipid profile of Wistar rats and we may suggest that the consumption of DA almonds or products prepared with them may be an effective option for the intake of healthy products.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Dipteryx / Aterosclerose Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: J Med Food Assunto da revista: CIENCIAS DA NUTRICAO / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Extratos Vegetais / Dipteryx / Aterosclerose Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans / Male Idioma: En Revista: J Med Food Assunto da revista: CIENCIAS DA NUTRICAO / MEDICINA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos