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Infection surveillance in pediatric hematopoietic stem cell transplantation recipients.
Caldas Teixeira, Daniela; Martins Oliveira Diniz, Lilian; Orlandi Mourão, Paulo Henrique; Kakehashi, Fabiana Maria; Vaz de Macedo, Antonio; Duani, Helena; Trindade Clemente, Wanessa; de Sá Rodrigues, Karla Emília; Maia de Castro Romanelli, Roberta.
Afiliação
  • Caldas Teixeira D; Hospital das Clinicas, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Martins Oliveira Diniz L; Hospital das Clinicas, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Orlandi Mourão PH; Pediatrics Department, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Kakehashi FM; Hospital das Clinicas, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Vaz de Macedo A; Hospital das Clinicas, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Duani H; Pediatrics Department, Faculty of Medicine, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Trindade Clemente W; Hospital das Clinicas, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • de Sá Rodrigues KE; Hospital das Clinicas, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
  • Maia de Castro Romanelli R; Hospital das Clinicas, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Eur J Haematol ; 100(1): 69-74, 2018 Jan.
Article em En | MEDLINE | ID: mdl-29032585
OBJECTIVE: To describe the profile of reported healthcare-associated infections (HAIs) in pediatric patients submitted to hematopoietic stem cell transplantation (HSCT) at a reference center. METHODS: Retrospective cohort of pediatric patients who were submitted to HSCT from 2008 to 2016. The criteria for HAI were based on those established by the National Healthcare Safety Network. Data were collected by active surveillance performed daily by professionals. This study was approved by the institutional research ethics committee. RESULTS: A total of 86 HSCTs were performed in 81 patients younger than 18 years of age (median, 10 years). Of these, 69 (85%) were males. Aplastic anemia and leukemia were the main diagnoses. A total of 140 HAIs were diagnosed with an incidence density of 28.2 infections/1000 patient-days. The most common HAI was laboratory-confirmed bloodstream infection (46), the majority of which was reported to be central venous catheter-associated (43). Gram-negative bacteria were the most prevalent microorganisms (58.5%). Almost all the infections occurred until 30 days after transplantation, and 17 deaths were observed within 180 days after the procedure. CONCLUSION: Active surveillance of HAIs in HSCT children allowed the evaluation of the incidence and profile of HAIs, which is essential for the health care of these patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecção Hospitalar / Transplante de Células-Tronco Hematopoéticas / Transplantados / Infecções Tipo de estudo: Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Aspecto: Ethics Limite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male País/Região como assunto: America do sul / Brasil Idioma: En Revista: Eur J Haematol Assunto da revista: HEMATOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecção Hospitalar / Transplante de Células-Tronco Hematopoéticas / Transplantados / Infecções Tipo de estudo: Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Screening_studies Aspecto: Ethics Limite: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male País/Região como assunto: America do sul / Brasil Idioma: En Revista: Eur J Haematol Assunto da revista: HEMATOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido