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Low-intensity LED therapy (λ 640 ± 20 nm) on saphenectomy healing in patients who underwent coronary artery bypass graft: a randomized, double-blind study.
de Barros Araújo Júnior, Raimundo; Gonzaga, Isabel Clarisse Albuquerque; Fernandes, Gilderlene Alves; Lima, Andréa Conceição Gomes; Cortelazzi, Paulo Sergio Tajra; de Oliveira, Rauirys Alencar; Nicolau, Renata Amadei.
Afiliação
  • de Barros Araújo Júnior R; Department of Cardiac Surgery, Santa Maria Hospital, University of Piauí State (UESPI), Rua Olavo Bilac 2335, Teresina, Piauí, 64001-280, Brazil. raimundodebarrosjunior@bol.com.br.
  • Gonzaga ICA; Lasertherapy and Photobiology Center, Research and Development Institute, IP&D, Universidade do Vale do Paraíba, UNIVAP, Avenida Shishima Hifumi, 2911, São José dos Campos, São Paulo, 12244-000, Brazil.
  • Fernandes GA; Uninovafapi College, Rua Vitorino Orthigues Fernandes 6123, Teresina, Piauí, 64003-505, Brazil.
  • Lima ACG; Lasertherapy and Photobiology Center, Research and Development Institute, IP&D, Universidade do Vale do Paraíba, UNIVAP, Avenida Shishima Hifumi, 2911, São José dos Campos, São Paulo, 12244-000, Brazil.
  • Cortelazzi PST; Uninovafapi College, Rua Vitorino Orthigues Fernandes 6123, Teresina, Piauí, 64003-505, Brazil.
  • de Oliveira RA; Lasertherapy and Photobiology Center, Research and Development Institute, IP&D, Universidade do Vale do Paraíba, UNIVAP, Avenida Shishima Hifumi, 2911, São José dos Campos, São Paulo, 12244-000, Brazil.
  • Nicolau RA; University of Piauí State (UESPI), Rua Olavo Bilac 2335, Teresina, Piauí, 64001-280, Brazil.
Lasers Med Sci ; 33(1): 103-109, 2018 Jan.
Article em En | MEDLINE | ID: mdl-29027034
Myocardial revascularization surgery (CABG) is the most appropriate treatment for coronary artery disease. Currently, the great challenge is to reduce postoperative complications, such as wound infections, dehiscence, pain, and patients' quality of life. The saphenectomy is the target of complications in 10% of cases, which can cause greater morbidity, time, and cost of hospitalization. Studies show that low-intensity laser or light-emitted diode (LED) therapy promotes positive biomodulation of the tissue repair process, culminating in a lower incidence of dehiscence, pain reduction, and improvement in quality of life. The objective of the present study was to evaluate clinically the saphenous tissue repair after LED therapy. Forty subjects of both genders who underwent CABG with extracorporeal circulation were randomly divided into two groups: the placebo (PG) and experimental (EG). The experimental group underwent low-intensity LED therapy (λ 640 ± 20 nm, 6 J/cm2) on saphenectomy. The tissue repair was analyzed by digital photogrammetry on the first and fifth postoperative day. The border closure was blindly evaluated by three researchers. The hematoma and hyperemia area was quantitatively analyzed using ImageJ© software. The results showed that in the experimental group, there were less bleeding points and no dehiscence in saphenectomy, as compared to the placebo group. There was also a smaller area of hematoma and hyperemia in the experimental group (p < 0.0009). These data lead to the conclusion that the type of phototherapy protocol employed can assist in tissue repair.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Veia Safena / Cicatrização / Ponte de Artéria Coronária / Terapia com Luz de Baixa Intensidade Tipo de estudo: Clinical_trials / Guideline Aspecto: Patient_preference Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Lasers Med Sci Assunto da revista: BIOTECNOLOGIA / RADIOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Veia Safena / Cicatrização / Ponte de Artéria Coronária / Terapia com Luz de Baixa Intensidade Tipo de estudo: Clinical_trials / Guideline Aspecto: Patient_preference Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Lasers Med Sci Assunto da revista: BIOTECNOLOGIA / RADIOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido