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En-Face Optical Coherence Tomography of Acute Syphilitic Posterior Placoid Chorioretinopathy.
Zett, Claudio; Lima, Luiz H; Vianello, Silvana; Ferreira, Adriano; de Andrade, Gabriel Costa; Farah, Michel E; Belfort, Rubens.
Afiliação
  • Zett C; a Department of Ophthalmology and Visual Science - Paulista School of Medicine , Federal University of São Paulo (UNIFESP) , São Paulo , Brazil.
  • Lima LH; b Department of Ophthalmology, Pontificia Universidad Católica de Valparaíso , Valparaíso , Chile.
  • Vianello S; a Department of Ophthalmology and Visual Science - Paulista School of Medicine , Federal University of São Paulo (UNIFESP) , São Paulo , Brazil.
  • Ferreira A; a Department of Ophthalmology and Visual Science - Paulista School of Medicine , Federal University of São Paulo (UNIFESP) , São Paulo , Brazil.
  • de Andrade GC; a Department of Ophthalmology and Visual Science - Paulista School of Medicine , Federal University of São Paulo (UNIFESP) , São Paulo , Brazil.
  • Farah ME; a Department of Ophthalmology and Visual Science - Paulista School of Medicine , Federal University of São Paulo (UNIFESP) , São Paulo , Brazil.
  • Belfort R; c Department of Ophthalmology, Instituto da Visão - IPEPO , São Paulo , Brazil.
Ocul Immunol Inflamm ; 26(8): 1264-1270, 2018.
Article em En | MEDLINE | ID: mdl-28976235
PURPOSE: To report a unique case series of acute syphilitic posterior placoid chorioretinopathy (ASPPC) correlating en-face optical coherence tomography (OCT) with standard imaging modalities. METHODS: In this retrospective case series, multimodal imaging was performed in three ASPPC patients at the time of disease presentation. RESULTS: Clinical and laboratory findings were consistent with the diagnosis of ASPPC. In all the study patients, multiple hyperreflective dot-like lesions distributed in the macular area and observed with en-face OCT at the level of retinal pigment epithelium (RPE) corresponded to the nodular RPE elevations on cross-sectional OCT and to the hyperautofluorescent spots on fundus autofluorescence. In addition, the cross-sectional OCT scans showed disorganization of the outer retinal bands and punctate choroidal hyperreflectivity. CONCLUSION: By combining en-face OCT with multimodal imaging analysis, we propose that a primary inflammation at the level of the choroid may be the pathogenic mechanism for the occurrence of outer retinal band abnormalities.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sífilis / Infecções Oculares Bacterianas / Coriorretinite / Tomografia de Coerência Óptica / Epitélio Pigmentado da Retina Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Ocul Immunol Inflamm Assunto da revista: ALERGIA E IMUNOLOGIA / OFTALMOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sífilis / Infecções Oculares Bacterianas / Coriorretinite / Tomografia de Coerência Óptica / Epitélio Pigmentado da Retina Tipo de estudo: Diagnostic_studies / Observational_studies Limite: Female / Humans / Male / Middle aged Idioma: En Revista: Ocul Immunol Inflamm Assunto da revista: ALERGIA E IMUNOLOGIA / OFTALMOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido