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CPAP and EPAP elicit similar lung deflation in a non-equivalent mode in GOLD 3-4 COPD patients.
Müller, Paulo de Tarso; Christofoletti, Gustavo; Koch, Rodrigo; Zardetti Nogueira, João Henrique; Patusco, Luiz Armando Pereira; Chiappa, Gaspar Rogério.
Afiliação
  • Müller PT; Federal University of Mato Grosso do Sul (UFMS)/Maria Aparecida Pedrossian Hospital (HUMAP), Laboratory of Respiratory Pathophysiology (LAFIR)/Division of Respiratory Medicine, Campo Grande, Mato Grosso do Sul, MS, Brazil.
  • Christofoletti G; Federal University of Mato Grosso do Sul (UFMS)/Maria Aparecida Pedrossian Hospital (HUMAP), Laboratory of Respiratory Pathophysiology (LAFIR)/Division of Respiratory Medicine, Campo Grande, Mato Grosso do Sul, MS, Brazil.
  • Koch R; Federal University of Mato Grosso do Sul (UFMS)/Maria Aparecida Pedrossian Hospital (HUMAP), Laboratory of Respiratory Pathophysiology (LAFIR)/Division of Respiratory Medicine, Campo Grande, Mato Grosso do Sul, MS, Brazil.
  • Zardetti Nogueira JH; Federal University of Mato Grosso do Sul (UFMS)/Maria Aparecida Pedrossian Hospital (HUMAP), Laboratory of Respiratory Pathophysiology (LAFIR)/Division of Respiratory Medicine, Campo Grande, Mato Grosso do Sul, MS, Brazil.
  • Patusco LAP; Federal University of Mato Grosso do Sul (UFMS)/Maria Aparecida Pedrossian Hospital (HUMAP), Laboratory of Respiratory Pathophysiology (LAFIR)/Division of Respiratory Medicine, Campo Grande, Mato Grosso do Sul, MS, Brazil.
  • Chiappa GR; Department of Physical Therapy, University of Brasilia (UnB), Brasilia, Brazil.
Clin Respir J ; 12(4): 1598-1606, 2018 Apr.
Article em En | MEDLINE | ID: mdl-28960914
INTRODUCTION: Lung hyperinflation is associated with inspiratory muscle strength reduction, nocturnal desaturation, dyspnea, altered cardiac function and poor exercise capacity in advanced COPD. OBJECTIVES: We investigated the responses of inspiratory capacity (IC) and inspiratory muscle strength (PImax), comparing continuous positive airway pressure (CPAP) and expiratory positive airway pressure (EPAP) with the main hypothesis that there would be similar effects on lung deflation. METHODS: Eligible patients were submitted to 10 cmH2 O CPAP and EPAP on different days, under careful ECG (HR) and peripheral oxygen saturation (SpO2 ) monitoring. RESULTS: Twenty-one eligible COPD patients were studied (13 male/8 female, FEV1 % predicted of 36.5 ± 9.8). Both CPAP and EPAP demonstrated significant post-pre (Δ) changes for IC and PImax, with mean ΔIC for CPAP and EPAP of 200 ± 100 mL and 170 ± 105 mL (P = .001 for both) in 13 and 12 patients (responders) respectively. There were similar changes in % predicted IC and PImax (∼7%, P = .001 for both) for responders and poor responder/non-responder agreement depending on CPAP/EPAP mode (Kappa = .113, P = .604). There were no differences in CPAP and EPAP regarding intensity of lung deflation (P =.254) and no difference was measured regarding HR (P = .235) or SpO2 (P = .111). CONCLUSIONS: Both CPAP and EPAP presented a similar effect on lung deflation, without guaranteeing that the response to one modality would be predictive of the response to the other.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Consumo de Oxigênio / Troca Gasosa Pulmonar / Capacidade Inspiratória / Ventilação com Pressão Positiva Intermitente / Doença Pulmonar Obstrutiva Crônica / Pressão Positiva Contínua nas Vias Aéreas / Pulmão Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Respir J Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Consumo de Oxigênio / Troca Gasosa Pulmonar / Capacidade Inspiratória / Ventilação com Pressão Positiva Intermitente / Doença Pulmonar Obstrutiva Crônica / Pressão Positiva Contínua nas Vias Aéreas / Pulmão Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Respir J Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Reino Unido