Synthesis of Ag@Fe2O3 nanocomposite based on O-carboxymethylchitosan with antimicrobial activity.
Int J Biol Macromol
; 107(Pt A): 42-51, 2018 Feb.
Article
em En
| MEDLINE
| ID: mdl-28870753
In this paper, nano-hybrid particles of Ag@Fe2O3 based on O-carboxymethylchitosan were successfully synthesized using different reducing agents (NaBH4, sucrose) and without reducing agent. The smallest silver nanoparticles were those prepared without reducing agent (â¼5±3nm). The average size of silver particles prepared with NaBH4 is around 5-15nm, and for samples prepared with sucrose, the average particle size is 10-25nm. The magnetization curves are roughly reversible, indicating that γ-Fe2O3 nanoparticles transit to a superparamagnetic state. Nanocomposites subjected to antimicrobial tests showed great antimicrobial activity against gram-positive (Staphylococcus aureus) and gram-negative (Escherichia coli) bacteria, and good activity against the yeast Candida albicans and resistant strains of Staphylococcus aureus. The antibacterial behavior as a function of time was investigated in microbial growth kinetics, and the best nanocomposite was the one without reducing agent, which completely inhibited microbial growth for 48h.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Quitosana
/
Nanopartículas Metálicas
/
Anti-Infecciosos
Idioma:
En
Revista:
Int J Biol Macromol
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Holanda