Need for pharmacogenetic studies on the prevalence of MTHFR mutations in Puerto Ricans and Hispanics.
Drug Metab Pers Ther
; 32(3): 169-171, 2017 09 26.
Article
em En
| MEDLINE
| ID: mdl-28862981
Methylenetetrahydrofolate reductase (MTHFR) mutations have been linked to many diseases. Evidence has been provided to prove that we need to perform pharmacogenetic studies regarding the prevalence of MTHFR mutations and diseases, risks, and the impact on folate requirement in general, but little has been published about Puerto Ricans. A multi center cross-sectional retrospective review study or a prospective pharmacogenetic study of valid genotypes and phenotypes of MTHFR mutations within the different populations of Puerto Ricans and Hispanics are recommended, because differences within them and within the general population are expected.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Farmacogenética
/
Metilenotetra-Hidrofolato Redutase (NADPH2)
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Limite:
Humans
País/Região como assunto:
Caribe
/
Puerto rico
Idioma:
En
Revista:
Drug Metab Pers Ther
Ano de publicação:
2017
Tipo de documento:
Article
País de publicação:
Alemanha