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New Delhi Metallo-Beta-Lactamase (NDM-1)-Producing Klebsiella Pneumoniae Isolated from a Burned Patient.
Petersen-Morfin, Santiago; Bocanegra-Ibarias, Paola; Morfin-Otero, Rayo; Garza-González, Elvira; Perez-Gomez, Hector Raul; González-Diaz, Esteban; Esparza-Ahumada, Sergio; León-Garnica, Gerardo; Amezcua-Salazar, Gabriel; Rodriguez-Noriega, Eduardo.
Afiliação
  • Petersen-Morfin S; Civil Hospital of Guadalajara, Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.
  • Bocanegra-Ibarias P; Department of Gastroenterology, University Hospital Dr. José Eleuterio González, Autonomous University of Nuevo Leon, Monterrey, Nuevo Leon, Mexico.
  • Morfin-Otero R; Civil Hospital of Guadalajara, Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.
  • Garza-González E; Institute of Infectious and Experimental Pathology, University Center of Health Sciences, University of Guadalajara, Guadalajara, Jalisco, Mexico.
  • Perez-Gomez HR; Department of Gastroenterology, University Hospital Dr. José Eleuterio González, Autonomous University of Nuevo Leon, Monterrey, Nuevo Leon, Mexico.
  • González-Diaz E; Civil Hospital of Guadalajara, Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.
  • Esparza-Ahumada S; Institute of Infectious and Experimental Pathology, University Center of Health Sciences, University of Guadalajara, Guadalajara, Jalisco, Mexico.
  • León-Garnica G; Civil Hospital of Guadalajara, Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.
  • Amezcua-Salazar G; Institute of Infectious and Experimental Pathology, University Center of Health Sciences, University of Guadalajara, Guadalajara, Jalisco, Mexico.
  • Rodriguez-Noriega E; Civil Hospital of Guadalajara, Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico.
Am J Case Rep ; 18: 805-809, 2017 Jul 18.
Article em En | MEDLINE | ID: mdl-28717120
BACKGROUND Infections affecting burn patients are frequently caused by Staphylococcus aureus, Pseudomonas aeruginosa, and Enterobacteriaceae species. Infections with these pathogens have become increasingly difficult to treat due to evolving antibiotic resistance mechanisms, including the production of carbapenemases. CASE REPORT The present case report describes the evolution of a burn patient with polymicrobial healthcare-associated burn infections, including a bloodstream infection due to an emergent multidrug-resistant New Delhi metallo-beta-lactamase (NDM-1)-producing Klebsiella pneumoniae. During hospitalization, initial antibiotic treatment eradicated some of the infecting species. Newer isolates were found to be multidrug-resistant and required unique antibiotic combinations. The patient's condition continued to deteriorate after the isolation of multidrug-resistant P. aeruginosa and NDM-1-positive K. pneumoniae from the blood. CONCLUSIONS This case report illustrates the need for adequate antibiotic therapies in burn patients with subsequent infections due to a carbapenemase-producing multidrug-resistant bacteria. The potential danger of new bacterial pathogens should be considered in this group of susceptible patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Beta-Lactamases / Queimaduras / Infecções por Klebsiella / Infecção Hospitalar / Bacteriemia / Klebsiella pneumoniae Limite: Adult / Humans / Male Idioma: En Revista: Am J Case Rep Ano de publicação: 2017 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Beta-Lactamases / Queimaduras / Infecções por Klebsiella / Infecção Hospitalar / Bacteriemia / Klebsiella pneumoniae Limite: Adult / Humans / Male Idioma: En Revista: Am J Case Rep Ano de publicação: 2017 Tipo de documento: Article País de afiliação: México País de publicação: Estados Unidos