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Disparities and Trends in Door-to-Needle Time: The FL-PR CReSD Study (Florida-Puerto Rico Collaboration to Reduce Stroke Disparities).
Oluwole, Sofia A; Wang, Kefeng; Dong, Chuanhui; Ciliberti-Vargas, Maria A; Gutierrez, Carolina M; Yi, Li; Romano, Jose G; Perez, Enmanuel; Tyson, Brittany Ann; Ayodele, Maranatha; Asdaghi, Negar; Gardener, Hannah; Rose, David Z; Garcia, Enid J; Zevallos, Juan Carlos; Foster, Dianne; Robichaux, Mary; Waddy, Salina P; Sacco, Ralph L; Rundek, Tatjana.
Afiliação
  • Oluwole SA; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Wang K; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Dong C; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Ciliberti-Vargas MA; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Gutierrez CM; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Yi L; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Romano JG; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Perez E; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Tyson BA; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Ayodele M; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Asdaghi N; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Gardener H; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Rose DZ; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Garcia EJ; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Zevallos JC; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Foster D; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Robichaux M; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Waddy SP; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Sacco RL; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
  • Rundek T; From the Department of Neurology, University of Miami Miller School of Medicine, FL (S.A.O., K.W., C.D., M.A.C.-V., C.M.G., L.Y., J.G.R., E.P., B.A.T., M.A., N.A., H.G., R.L.S., T.R.); Department of Neurology, University of South Florida Morsani College of Medicine, Tampa (D.Z.R.); National Institut
Stroke ; 48(8): 2192-2197, 2017 08.
Article em En | MEDLINE | ID: mdl-28706119
BACKGROUND AND PURPOSE: In the United States, about half of acute ischemic stroke patients treated with tPA (tissue-type plasminogen activator) receive treatment within 60 minutes of hospital arrival. We aimed to determine the proportion of patients receiving tPA within 60 minutes (door-to-needle time [DTNT] ≤60) and 45 minutes (DTNT ≤45) of hospital arrival by race/ethnicity and sex and to identify temporal trends in DTNT ≤60 and DTNT ≤45. METHODS: Among 65 654 acute ischemic stroke admissions in the National Institute of Neurological Disorders and Stroke-funded FL-PR CReSD study (Florida-Puerto Rico Collaboration to Reduce Stroke Disparities) from 2010 to 2015, we included 6181 intravenous tPA-treated cases (9.4%). Generalized estimating equations were used to determine predictors of DTNT ≤60 and DTNT ≤45. RESULTS: DTNT ≤60 was achieved in 42% and DTNT ≤45 in 18% of cases. After adjustment, women less likely received DTNT ≤60 (odds ratio, 0.81; 95% confidence interval, 0.72-0.92) and DTNT ≤45 (odds ratio, 0.73; 95% confidence interval, 0.57-0.93). Compared with Whites, Blacks less likely had DTNT ≤45 during off hours (odds ratio, 0.68; 95% confidence interval, 0.47-0.98). Achievement of DTNT ≤60 and DTNT ≤45 was highest in South Florida (50%, 23%) and lowest in West Central Florida (28%, 11%). CONCLUSIONS: In the FL-PR CReSD, achievement of DTNT ≤60 and DTNT ≤45 remains low. Compared with Whites, Blacks less likely receive tPA treatment within 45 minutes during off hours. Treatment within 60 and 45 minutes is lower in women compared with men and lowest in West Central Florida compared with other Florida regions and Puerto Rico. Further research is needed to identify reasons for delayed thrombolytic treatment in women and Blacks and factors contributing to regional disparities in DTNT.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia Trombolítica / Ativador de Plasminogênio Tecidual / Acidente Vascular Cerebral / Disparidades em Assistência à Saúde / Tempo para o Tratamento Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Limite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do norte / Caribe / Puerto rico Idioma: En Revista: Stroke Ano de publicação: 2017 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Terapia Trombolítica / Ativador de Plasminogênio Tecidual / Acidente Vascular Cerebral / Disparidades em Assistência à Saúde / Tempo para o Tratamento Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Determinantes_sociais_saude Limite: Aged / Aged80 / Female / Humans / Male / Middle aged País/Região como assunto: America do norte / Caribe / Puerto rico Idioma: En Revista: Stroke Ano de publicação: 2017 Tipo de documento: Article País de publicação: Estados Unidos