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Multinodular and Vacuolating Neuronal Tumor of the Cerebrum: A New "Leave Me Alone" Lesion with a Characteristic Imaging Pattern.
Nunes, R H; Hsu, C C; da Rocha, A J; do Amaral, L L F; Godoy, L F S; Watkins, T W; Marussi, V H; Warmuth-Metz, M; Alves, H C; Goncalves, F G; Kleinschmidt-DeMasters, B K; Osborn, A G.
Afiliação
  • Nunes RH; From the Division of Neuroradiology (R.H.N., A.J.d.R., L.L.F.d.A., H.C.A.), Santa Casa de Sao Paulo School of Medical Sciences, Sao Paulo, Brazil renatohn@hotmail.com.
  • Hsu CC; Division of Neuroradiology (R.H.N., A.J.d.R.), Diagnosticos da America SA, Sao Paulo, Brazil.
  • da Rocha AJ; Department of Medical Imaging (C.C.H., T.W.W.), Princess Alexandra Hospital, Brisbane, Queensland, Australia.
  • do Amaral LLF; From the Division of Neuroradiology (R.H.N., A.J.d.R., L.L.F.d.A., H.C.A.), Santa Casa de Sao Paulo School of Medical Sciences, Sao Paulo, Brazil.
  • Godoy LFS; Division of Neuroradiology (R.H.N., A.J.d.R.), Diagnosticos da America SA, Sao Paulo, Brazil.
  • Watkins TW; From the Division of Neuroradiology (R.H.N., A.J.d.R., L.L.F.d.A., H.C.A.), Santa Casa de Sao Paulo School of Medical Sciences, Sao Paulo, Brazil.
  • Marussi VH; Division of Neuroradiology (L.L.F.d.A., V.H.M.), Medimagem, Hospital da Beneficencia Portuguesa de Sao Paulo, Sao Paulo, Brazil.
  • Warmuth-Metz M; Department of Radiology (L.F.S.G.), Hospital Sirio Libanes, Sao Paulo, Brazil.
  • Alves HC; Department of Radiology (L.F.S.G.), Medical School, Universidade de Sao Paulo, Sao Paulo, Brazil.
  • Goncalves FG; Department of Medical Imaging (C.C.H., T.W.W.), Princess Alexandra Hospital, Brisbane, Queensland, Australia.
  • Kleinschmidt-DeMasters BK; Division of Neuroradiology (L.L.F.d.A., V.H.M.), Medimagem, Hospital da Beneficencia Portuguesa de Sao Paulo, Sao Paulo, Brazil.
  • Osborn AG; Department of Neuroradiology (M.W.-M.), University Hospital Würzburg, Würzburg, Germany.
AJNR Am J Neuroradiol ; 38(10): 1899-1904, 2017 Oct.
Article em En | MEDLINE | ID: mdl-28705817
Multinodular and vacuolating neuronal tumor of the cerebrum is a recently reported benign, mixed glial neuronal lesion that is included in the 2016 updated World Health Organization classification of brain neoplasms as a unique cytoarchitectural pattern of gangliocytoma. We report 33 cases of presumed multinodular and vacuolating neuronal tumor of the cerebrum that exhibit a remarkably similar pattern of imaging findings consisting of a subcortical cluster of nodular lesions located on the inner surface of an otherwise normal-appearing cortex, principally within the deep cortical ribbon and superficial subcortical white matter, which is hyperintense on FLAIR. Only 4 of our cases are biopsy-proven because most were asymptomatic and incidentally discovered. The remaining were followed for a minimum of 24 months (mean, 3 years) without interval change. We demonstrate that these are benign, nonaggressive lesions that do not require biopsy in asymptomatic patients and behave more like a malformative process than a true neoplasm.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Ganglioneuroma Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: AJNR Am J Neuroradiol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Encefálicas / Ganglioneuroma Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: AJNR Am J Neuroradiol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Brasil País de publicação: Estados Unidos