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Recent advances in the management of rectal cancer: No surgery, minimal surgery or minimally invasive surgery.
Plummer, Joseph M; Leake, Pierre-Anthony; Albert, Matthew R.
Afiliação
  • Plummer JM; Joseph M Plummer, Pierre-Anthony Leake, Department of Surgery, Radiology, Anaesthesia and Intensive Care, University of the West Indies, Kingston 7, Jamaica.
  • Leake PA; Joseph M Plummer, Pierre-Anthony Leake, Department of Surgery, Radiology, Anaesthesia and Intensive Care, University of the West Indies, Kingston 7, Jamaica.
  • Albert MR; Joseph M Plummer, Pierre-Anthony Leake, Department of Surgery, Radiology, Anaesthesia and Intensive Care, University of the West Indies, Kingston 7, Jamaica.
World J Gastrointest Surg ; 9(6): 139-148, 2017 Jun 27.
Article em En | MEDLINE | ID: mdl-28690773
Over the last decade, with the acceptance of the need for improvements in the outcome of patients affected with rectal cancer, there has been a significant increase in the literature regarding treatment options available to patients affected by this disease. That treatment related decisions should be made at a high volume multidisciplinary tumor board, after pre-operative rectal magnetic resonance imaging and the importance of total mesorectal excision (TME) are accepted standard of care. More controversial is the emerging role for watchful waiting rather than radical surgery in complete pathologic responders, which may be appropriate in 20% of patients. Patients with early T1 rectal cancers and favorable pathologic features can be cured with local excision only, with transanal minimal invasive surgery (TAMIS) because of its versatility and almost universal availability of the necessary equipment and skillset in the average laparoscopic surgeon, emerging as the leading option. Recent trials have raised concerns about the oncologic outcomes of the standard "top-down" TME hence transanal TME (TaTME "bottom-up") approach has gained popularity as an alternative. The challenges are many, with a dearth of evidence of the oncologic superiority in the long-term for any given option. However, this review highlights recent advances in the role of chemoradiation only for complete pathologic responders, TAMIS for highly selected early rectal cancer patients and TaTME as options to improve cure rates whilst maintaining quality of life in these patients, while we await the results of further definitive trials being currently conducted.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Aspecto: Patient_preference Idioma: En Revista: World J Gastrointest Surg Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Jamaica País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Aspecto: Patient_preference Idioma: En Revista: World J Gastrointest Surg Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Jamaica País de publicação: Estados Unidos