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25 (OH) D3 levels, incidence and recurrence of different clinical forms of benig paroxysmal positional vertigo.
Maslovara, Sinisa; Butkovic Soldo, Silva; Sestak, Anamarija; Milinkovic, Katarina; Rogic-Namacinski, Jasna; Soldo, Anamarija.
Afiliação
  • Maslovara S; County General Hospital, Department of Otolaryngology, Vukovar, Croatia; University of Osijek, Medical Faculty, Department of Otorhinolaryngology and Maxillofacial Surgery, Osijek, Croatia. Electronic address: sinisamaslovara@yahoo.com.
  • Butkovic Soldo S; Clinical Hospital Center, Department of Neurology, Osijek, Croatia; University of Osijek, Medical Faculty, Department of Neurology, Osijek, Croatia.
  • Sestak A; County General Hospital, Department of Otolaryngology, Vukovar, Croatia.
  • Milinkovic K; County General Hospital, Department of Otolaryngology, Vukovar, Croatia.
  • Rogic-Namacinski J; County General Hospital, Department of Otolaryngology, Vukovar, Croatia; County General Hospital, Department of Laboratory Diagnostic, Vukovar, Croatia.
  • Soldo A; Clinical Hospital Center, Department of Neurology, Osijek, Croatia; University of Osijek, Medical Faculty, Department of Neurology, Osijek, Croatia.
Braz J Otorhinolaryngol ; 84(4): 453-459, 2018.
Article em En | MEDLINE | ID: mdl-28655524
INTRODUCTION: Benign paroxysmal positional vertigo is the most common cause of dizziness in the general population. It is a condition with potential impact of reduced levels of vitamin D on its recurrent attacks. OBJECTIVES: The aim of this study was to measure the serum levels of 25-hydroxyvitamin D3 (25-OH D3) in patients with benign paroxysmal positional vertigo and determine whether there is a difference in the serum levels of vitamin D3 between patients with and without recurrence, as well as between the different clinical forms of benign paroxysmal positional vertigo. METHODS: The study included 40 patients who came to the regular medical examination, diagnosed with posterior canal-benign paroxysmal positional vertigo based on the positive Dix-Hallpike's test. All patients underwent Epley manoeuvre after the diagnosis. Patients were classified according to current guidelines for levels of vitamin D3 in the serum in three groups: the deficiency, insufficiency and adequate level. RESULTS: The average serum level of 25-OH D3 among respondents was 20.78ng/mL, indicating a lack or insufficiency of the aforementioned 25-OH D3. According to the levels of 25-OH D3, most patients suffer from deficiency (47.5%). 7 (17.5%) respondents had adequate blood level of 25-OH D3, and 14 (35%) respondents suffer from insufficiency. A significant difference was not found in the serum level of 25-OH D3 between patients with and without benign paroxysmal positional vertigo recurrence. There was a significant difference in the serum levels of 25-OH D3 in comparison to the clinical form of the disease. Lower 25-OH D3 values were found in patients with canalithiasis compared to those with cupulolithiasis. CONCLUSIONS: There were no significant differences in the vitamin D3 serum level in patients with and without recurrence. The study showed a low level of serum vitamin D3 in most patients, indicating the need for supplemental therapy.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Calcifediol / Colecalciferol / Vertigem Posicional Paroxística Benigna Tipo de estudo: Guideline / Incidence_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Braz J Otorhinolaryngol Assunto da revista: OTORRINOLARINGOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Calcifediol / Colecalciferol / Vertigem Posicional Paroxística Benigna Tipo de estudo: Guideline / Incidence_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Braz J Otorhinolaryngol Assunto da revista: OTORRINOLARINGOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de publicação: Brasil