Your browser doesn't support javascript.
loading
[Strategies to reduce infections and antibiotic use and its effects in a neonatal care unit]. / Estrategias para reducir infecciones, uso de antimicrobianos y sus efectos en una unidad de neonatología.
Urzúa, Soledad; Ferrés, Marcela; García, Patricia; Sánchez, Amparo; Luco, Matías.
Afiliação
  • Urzúa S; Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Ferrés M; Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • García P; Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Sánchez A; Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
  • Luco M; Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Rev Chilena Infectol ; 34(2): 99-107, 2017 Apr.
Article em Es | MEDLINE | ID: mdl-28632822
INTRODUCTION: Late onset sepsis (LOS) remains an important cause of morbidity and mortality in neonatal intensive care units (NICU). The empirical use of vancomycin and other broad spectrum antibiotics is very frequent and is associated with the emergence of resistant agents, infection by gram-negative bacilli (GNB), fungal infections and increased morbidity and mortality. OBJECTIVE: To evaluate the impact of 5 intervention protocols designed to reduce infections and promote the rational use of antibiotics (AB) in a single NICU. PATIENTS AND METHOD: Retrospective analysis included all hospitalized patients before (year 2012) and after interventions (August 2013 through July 2014). All episodes of positive cultures (blood, urine, tracheal and spinal fluid) were considered as late onset infections. RESULTS: After intervention, a significant decrease of late onset infections was observed from 14.3 to 8.5 per 1,000 live births (p < 0.01); with a decrease in LOS from 5.7 to 2.9 per 1,000 live births, although no significant. There was a decrease in vancomycin and 3rd generation cephalosporin use without Candida spp infections in the intervention period. Mortality rates and length of hospital stay were similar in both study periods. CONCLUSION: After interventions, there was an important reduction in overall late onset infections and AB related costs.
Assuntos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Unidades de Terapia Intensiva Neonatal / Infecção Hospitalar / Controle de Infecções / Antibacterianos Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Newborn País/Região como assunto: America do sul / Chile Idioma: Es Revista: Rev Chilena Infectol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Chile País de publicação: Chile
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções Bacterianas / Unidades de Terapia Intensiva Neonatal / Infecção Hospitalar / Controle de Infecções / Antibacterianos Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Newborn País/Região como assunto: America do sul / Chile Idioma: Es Revista: Rev Chilena Infectol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Chile País de publicação: Chile