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Multiple sclerosis in Latin America: A different disease course severity? A collaborative study from the MSBase Registry.
Rojas, Juan Ignacio; Patrucco, Liliana; Trojano, Maria; Lugaresi, Alessandra; Izquierdo, Guillermo; Butzkueven, Helmut; Jokubaitis, Vilija; Duquette, Pierre; Girard, Marc; Grand'Maison, Francois; Grammond, Pierre; Oreja-Guevara, Celia; Hupperts, Raymond; Boz, Cavit; Petersen, Thor; Bergamaschi, Roberto; Giuliani, Giorgio; Lechner-Scott, Jeannette; Barnett, Michael; Rio, Maria Edite; Van Pesch, Vincent; Amato, Maria Pia; Iuliano, Gerardo; Fiol, Marcela; Slee, Mark; Verheul, Freek; Fernandez-Bolanos, Ricardo; Poehlau, Dieter; Saladino, Maria Laura; Braber-Moerland, Leontien Den; Deri, Norma; Oleschko-Arruda, Walter; Cabrera-Gomez, Jose Antonio; Paine, Mark; Vella, Norbert; Kister, Ilya; Skromne, Eli; Savino, Aldo; Shaw, Cameron; Moore, Fraser; Vucic, Steve; Petkovska-Boskova, Tatjana; Bacile, Elizabeth Alejandra Bacile; Santiago, Vetere; Cristiano, Edgardo.
Afiliação
  • Rojas JI; Multiple Sclerosis Center, Hospital Italiano, Argentina.
  • Patrucco L; Multiple Sclerosis Center, Hospital Italiano, Argentina.
  • Trojano M; Department of Basic Medical Sciences, Neuroscience, and Sense Organs, University of Bari, Italy.
  • Lugaresi A; MS Center, Department of Neuroscience, Imaging, and Clinical Sciences, University G. d'Annunzio, Italy.
  • Izquierdo G; Department of Neurology, Hospital Universitario Virgen Macarena, Spain.
  • Jokubaitis V; Department of Neurology, Royal Melbourne Hospital, Australia; Department of Medicine, University of Melbourne, Melbourne, Australia; Department of Neurology, Box Hill Hospital, Monash University, Australia.
  • Girard M; Department of Neurology, Hôpital Notre Dame, Canada.
  • Grand'Maison F; Neuro Rive-Sud, Hôpital Charles LeMoyne, Canada.
  • Grammond P; Department of Neurology, Hotel-Dieu de Lévis, Canada.
  • Oreja-Guevara C; Multiple Sclerosis Unit, University Hospital San Carlos, Spain.
  • Hupperts R; Department of Neurology, Orbis Medical Center, The Netherlands.
  • Boz C; Karadeniz Technical University, Turkey.
  • Petersen T; Aarhus University Hospital, Denmark.
  • Bergamaschi R; National Neurological Institute C. Mondino, Italy.
  • Giuliani G; Ospedale di Macerata, Italy.
  • Lechner-Scott J; Department of Medicine, John Hunter Hospital, Australia; Hunter Medical Research Institute, University of Newcastle, Australia.
  • Barnett M; Brain and Mind Research Institute, Australia.
  • Rio ME; Hospital S. Joao, Portugal.
  • Van Pesch V; Department of Neurology, Cliniques Universitaires Saint-Luc, Belgium.
  • Amato MP; Department NEUROFARBA, Section of Neurosciences, University of Florence, Italy.
  • Iuliano G; Department of Neurology, Ospedali Riuniti di Salerno, Italy.
  • Fiol M; FLENI, Argentina.
  • Slee M; Flinders University and Medical Centre, Australia.
  • Verheul F; Neurology Unit, Groen Hart Ziekenhuis, The Netherlands.
  • Fernandez-Bolanos R; Department of Neurology, Hospital Universitario Virgen de Valme, Spain.
  • Poehlau D; Multiple Sclerosis Centre Kamillus-Klinik, Germany.
  • Saladino ML; INEBA, Argentina.
  • Braber-Moerland LD; Francicus Ziekenhuis, The Netherlands.
  • Deri N; Hospital Fernandez, Argentina.
  • Oleschko-Arruda W; Hospital Ecoville, Brazil.
  • Cabrera-Gomez JA; Centro Internacional de Restauracion Neurologica, Cuba.
  • Paine M; St Vincent's Hospital, Australia.
  • Vella N; Mater Dei Hospital, Malta.
  • Kister I; New York University Langone Medical Center, USA.
  • Skromne E; Hospital de Especialidades, Centro Medico Nacional Siglo XXI, Mexico.
  • Savino A; Consultorio Privado, Argentina.
  • Shaw C; Geelong Hospital, Australia.
  • Moore F; Jewish General Hospital, Canada.
  • Vucic S; Westmead Hospital, Australia.
  • Petkovska-Boskova T; Clinic of Neurology Clinical Center, Macedonia.
  • Bacile EAB; Instituto de Neurociencias Cordoba, Argentina.
  • Santiago V; HIGA Gral, Argentina.
  • Cristiano E; Multiple Sclerosis Center, Hospital Italiano, Argentina.
Mult Scler J Exp Transl Clin ; 1: 2055217315600193, 2015.
Article em En | MEDLINE | ID: mdl-28607702
Limited data suggest that multiple sclerosis (MS) in Latin America (LA) could be less severe than in the rest of the world. The objective was to compare the course of MS between LA and other regions. METHODS: Centers from 18 countries with >20 cases enrolled in the MSBase Registry participated. Patients with MS with a disease duration of >1 year and <30 years at time of EDSS measurement were evaluated. The MS Severity Score (MSSS) was used as a measure of disease progression. Comparisons among regions (North America, Europe, Australia and LA), hemispheres and countries were performed. RESULTS: A total of 9610 patients were included. Patients were from: Europe, 6290 (65.6%); North America, 1609 (16.7%); Australia, 1119 (11.6%); and LA, 592 (6.1%). The mean MSSS in patients from LA was 4.47 ± 2.8, 4.53 ± 2.8 in North America, 4.51 ± 2.8 in Europe and 4.49 ± 2.7 in Australia. Mean MSSS in the northern hemisphere was 4.51 ± 1.6 compared to 4.48 ± 1.9 in the southern hemisphere. No differences were found for MSSS among hemispheres (p = 0.68), regions (p = 0.96) or countries (p = 0.50). CONCLUSIONS: Our analyses did not discover any difference in mean MSSS among patients from different regions, hemispheres or countries.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Mult Scler J Exp Transl Clin Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Argentina País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Mult Scler J Exp Transl Clin Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Argentina País de publicação: Estados Unidos