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Intravenous palivizumab in respiratory syncytial virus infection after hematopoietic stem cell transplant in children.
Torres, Juan Pablo; Tapia, Lorena I; Catalán, Paula; De la Maza, Verónica; Mejías, Asunción.
Afiliação
  • Torres JP; Department of Pediatrics, Division of Pediatric Infectious Diseases, Hospital Luis Calvo Mackenna, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
  • Tapia LI; Department of Pediatrics and Pediatric Surgery, Hospital Roberto del Río and Virology Program, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
  • Catalán P; Transplant Unit, Hospital Luis Calvo Mackenna, Santiago, Chile.
  • De la Maza V; Department of Pediatrics, Division of Pediatric Infectious Diseases, Hospital Luis Calvo Mackenna, Facultad de Medicina, Universidad de Chile, Santiago, Chile.
  • Mejías A; Division of Pediatric Infectious Diseases, Nationwide Children's Hospital, The Ohio State University, Columbus, OH.
Pediatr Blood Cancer ; 64(12)2017 Dec.
Article em En | MEDLINE | ID: mdl-28598593
Respiratory syncytial virus (RSV) infection can cause lower respiratory tract disease and mortality in pediatric hematopoietic stem cell transplant (HSCT) recipients. We report two children who underwent HSCT and developed RSV infection simultaneously at the Bone Marrow Transplant Unit. The treatment with intravenous palivizumab was provided and sequential viral loads were measured in nasopharyngeal (NP) and whole blood samples. To our knowledge, this is the first report where RSV loads were measured in parallel (NP and blood), before and after palivizumab, in correlation with a favorable clinical outcome in both cases.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Infecções por Vírus Respiratório Sincicial / Transplante de Células-Tronco Hematopoéticas / Palivizumab Limite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Pediatr Blood Cancer Assunto da revista: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Chile País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Infecções por Vírus Respiratório Sincicial / Transplante de Células-Tronco Hematopoéticas / Palivizumab Limite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Pediatr Blood Cancer Assunto da revista: HEMATOLOGIA / NEOPLASIAS / PEDIATRIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Chile País de publicação: Estados Unidos