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[Hepatocellular carcinoma]. / Carcinoma hepatocelular.
Gonçalves, C S; Pereira, F E; Zago, M da P.
Afiliação
  • Gonçalves CS; Departamento da Clínica Médica e de Patologia do Centro Biomédico da Universidade Federal do Espírito Santo e Serviços de Gastroenterologia e de Patologia do Hospital Universitário Cassiano Antonio de Moraes, Vitória, ES.
Arq Gastroenterol ; 25(4): 207-17, 1988.
Article em Pt | MEDLINE | ID: mdl-2855822
Hepatocellular carcinoma (HCC), one of the most frequent tumors in the world, is included by the World Health Organization as a relevant public health problem in areas of high incidence as Africa and Southeast of Asia. In this review it will be discussed: a) the close relationship between HCC and hepatitis B virus (HBV), the more universal but not the single etiologic factor having other carcinogens and co-carcinogens involved with the origen of the tumor; b) the great variation in geographic distribution of this tumor, including that of Brazil where the incidence of HCC, including the new macroscopic classification according to the pattern of growth and general with liver cirrhosis in all countries where the tumor is diagnosed; d) some morphological aspects of HCC, including the new macroscopic classification according to the pattern of growth and general characteristics of small HCC; e) the clinical and biochemical aspects, calling attention to the evaluation of serum levels of alpha-fetoprotein, not always increased in patients with HCC, and the immage processing methods, specially ultrassonography, as methods for early diagnosis of HCC, being relevant in the follow-up of high risk patients (cirrhotics HBsAg (+]. Finally some comments are done about the therapeutic methods and perspectives of reduction in the incidence of the tumor with the use of vaccination against HBV infection.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudo: Diagnostic_studies / Etiology_studies / Screening_studies Limite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: Pt Revista: Arq Gastroenterol Ano de publicação: 1988 Tipo de documento: Article País de publicação: Brasil
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudo: Diagnostic_studies / Etiology_studies / Screening_studies Limite: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged Idioma: Pt Revista: Arq Gastroenterol Ano de publicação: 1988 Tipo de documento: Article País de publicação: Brasil