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Gastrointestinal cytomegalovirus disease in a patient with pemphigus vulgaris treated with corticosteroid and mycophenolate mofetil.
Oliveira, Luiza Barbosa; Maruta, Celina Wakisaka; Miyamoto, Denise; Salvadori, Fernanda Aburesi; Santi, Claudia Giuli; Aoki, Valeria; Duarte-Neto, Amaro Nunes.
Afiliação
  • Oliveira LB; Autopsy Division - Anatomic Pathology Department - Faculty of Medicine - Universidade de São Paulo, São Paulo/SP - Brazil.
  • Maruta CW; Department of Dermatology - Faculty of Medicine - Universidade de São Paulo, São Paulo/SP - Brazil.
  • Miyamoto D; Department of Dermatology - Faculty of Medicine - Universidade de São Paulo, São Paulo/SP - Brazil.
  • Salvadori FA; Emergency Department - Hospital das Clínicas - Faculty of Medicine - Universidade de São Paulo, São Paulo/SP - Brazil.
  • Santi CG; Department of Dermatology - Faculty of Medicine - Universidade de São Paulo, São Paulo/SP - Brazil.
  • Aoki V; Department of Dermatology - Faculty of Medicine - Universidade de São Paulo, São Paulo/SP - Brazil.
  • Duarte-Neto AN; Autopsy Division - Anatomic Pathology Department - Faculty of Medicine - Universidade de São Paulo, São Paulo/SP - Brazil.
Autops Case Rep ; 7(1): 23-30, 2017.
Article em En | MEDLINE | ID: mdl-28536684
Pemphigus vulgaris is an autoimmune disease characterized by the formation of suprabasal intra-epidermal blisters on the skin and mucosal surfaces. Infectious diseases are the main cause of death in patients with pemphigus due to the disrupture of the physiological skin barrier, immune dysregulation, and the use of immunosuppressive medications leaving the patient prone to acquire opportunistic infections. We report the case of a 67-year-old woman diagnosed with pemphigus vulgaris, who was irregularly taking prednisone and mycophenolate mofetil. She was hospitalized because of a 1-month history of watery diarrhea and oral ulcers. Unfortunately, the patient died suddenly on the ward. The autopsy revealed a bilateral saddle pulmonary embolism, Gram-positive cocci bronchopneumonia, and gastrointestinal cytomegalovirus infection, causing extensive gastrointestinal mucosal ulcers.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Autops Case Rep Ano de publicação: 2017 Tipo de documento: Article País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Autops Case Rep Ano de publicação: 2017 Tipo de documento: Article País de publicação: Brasil