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Premorbid History of Major Depression and the Depressive Syndrome of Alzheimer's Disease.
Zubenko, George S; Rifai, Ph D A Hind; Mulsant, Benoit H; Sweet, Robert A; Pasternak, Rona E.
Afiliação
  • Zubenko GS; Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA.
  • Rifai PDAH; Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA.
  • Mulsant BH; Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA.
  • Sweet RA; Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA.
  • Pasternak RE; Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Am J Geriatr Psychiatry ; 4(1): 85-90, 1996.
Article em En | MEDLINE | ID: mdl-28531059
To test the hypothesis that primary degenerative dementia of the Alzheimer type (PDD-AT) may increase the likelihood of expression of a lifetime vulnerability to the development of depression, the authors compared the premorbid rates of major depression in psychiatric inpatients with dementia, with or without a concurrent syndrome of depression. A premorbid history of major depression was four times more common in patients with the depressive syndrome of PDD-AT than in PDD-AT patients without depression. The authors discuss the significance of these findings for pathophysiologic models and estimates of comorbidity of depression in PDD-AT.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Am J Geriatr Psychiatry Assunto da revista: GERIATRIA / PSIQUIATRIA Ano de publicação: 1996 Tipo de documento: Article País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Am J Geriatr Psychiatry Assunto da revista: GERIATRIA / PSIQUIATRIA Ano de publicação: 1996 Tipo de documento: Article País de publicação: Reino Unido